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NCT00000429 · ClinicalTrials.gov registry record · Phase 2
Calcium Supplements for Bone Health in Juvenile Rheumatoid Arthritis
A Phase 2 study, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- Phase 2
- Development phase
- 192
- Enrollment target
NCT00000429: Completed Phase 2 study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT00000429 is a Phase 2 study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 192 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000429, a Phase 2 study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 192 participants
- Enrollment target
Study Summary
This study looks at the effects of taking calcium pills on bone health in young people with juvenile rheumatoid arthritis (JRA). In this 2-year study, children aged 6-18 who have JRA will take either a calcium supplement or a matching placebo (inactive or "dummy" pill) containing no calcium. During the study, researchers and patients will not know if a patient is taking calcium or placebo. We believe that patients who take calcium supplements will have at least a 10 percent greater increase in total body bone mineral density compared to patients who take the placebo. We will evaluate patients at Children's Hospital Medical Center every 6 months for 2 years. During this 2-year period, participants in the study will take one multivitamin containing 400 IU (international units) of vitamin D and either 1,000 mg of calcium carbonate (Tums tablets) by mouth or a matching placebo once a day. We will check patients 6 and 18 months after the 2-year treatment period to find out if people in the Tums-treated group maintain any increases in bone formation that occurred during the 2-year treatment period.
Interventions
- DRUG Calcium carbonate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 1996-06 |
| Est. Completion | 2001-05 |
| Phase | Phase 2 |
What the finished NCT00000429 record still lists
NCT00000429 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher).
The record links to 0 conditions, and to 1 intervention - of which Calcium carbonate is the first listed.
NCT00000429 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000429 about?
NCT00000429 is a clinical study titled "Calcium Supplements for Bone Health in Juvenile Rheumatoid Arthritis". This study looks at the effects of taking calcium pills on bone health in young people with juvenile rheumatoid arthritis (JRA). In this 2-year study, children aged 6-18 who have JRA will take either a calcium supplement or a matching placebo (inactive or "dummy" pill) containing no calcium. During ...
What is the current status of trial NCT00000429?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 192 participants. The study started on 1996-06. Estimated completion is 2001-05.
What interventions are being tested in trial NCT00000429?
The interventions under investigation include: Calcium carbonate (DRUG).
Who is sponsoring clinical trial NCT00000429?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000429's enrollment target sits among peer trials
192 352nd of 2000 higher than 1,648 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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