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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Venous Insufficiency: early-phase trial registry

2 of 10 indexed Venous Insufficiency trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 2 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Venous Insufficiency: 10 US clinical trials tracked, 2 recruiting.

Venous Insufficiency is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 2 of these trials.

Enrollment posture brief

Registry condition venous-insufficiency

OPEN 2 | RECR 20% | LATE 0 | EARLY 2 | RANK #1724 | SPON 2

Nearest open-share peer: Acral Lentiginous Melanoma (20% recruiting · 5 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%Venous Insufficiency (this)20%
Open-enrollment share among volume-matched conditions near Venous Insufficiency

Venous Insufficiency lists 2 open slots (20% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Venous Insufficiency on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Venous Insufficiency is recruiting below its size-band peers.

    2 of 10 indexed trials (20%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Venous Insufficiency research.

    Medical University of South Carolina accounts for 2 of 10 trials (20%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Venous Insufficiency trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 10 trials that report a genuine target (sentinel values excluded). 6 of those (60%) plan for fewer than 100 participants.

  4. Venous Insufficiency research is mostly interventional.

    9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21

Open and recent trials

10 total, page 1 of 1

RECRUITING NA 60 participants

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

BioStem Technologies

NCT06811909

RECRUITING NA 50 participants

The ROle of Compression StocKings in Heart Failure Patients

University of Maryland, Baltimore

NCT06350695

ACTIVE NOT RECRUITING NA 225 participants

Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)

Washington University School of Medicine

NCT03250247

COMPLETED 547 participants

Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation

Lake Washington Vascular

NCT04006184

COMPLETED Phase 1 197 participants

Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation

Medical University of South Carolina

NCT01509599

COMPLETED Phase 2 140 participants

Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence

Medical University of South Carolina

NCT02626156

COMPLETED NA 60 participants

Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children.

Boston Children's Hospital

NCT02324504

COMPLETED NA 44 participants

Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings

Johns Hopkins University

NCT01793194

COMPLETED NA 28 participants

Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)

Tactile Medical

NCT02395302

COMPLETED NA 12 participants

Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS)

University of North Carolina, Chapel Hill

NCT00858130

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Named interventions

Most-linked intervention names on Venous Insufficiency records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Dual Action Pneumatic Compression Device
1 trials
Compression Stockings Other
1 trials
C3 Wave ECG-based PICC Tip Confirmation System Device
1 trials
VeinOPlus Device
1 trials
Usual care Procedure
1 trials
Cryotherapy: Cooling gel wrap Procedure
1 trials
Cooling cotton pack Device
1 trials
Cooling gel pack Device
1 trials

US sites by state

Facility locations filed on Venous Insufficiency trials. A trial with sites in several states counts in each.

Massachusetts 3 trials
California 3 trials
South Carolina 2 trials
New York 2 trials
North Carolina 2 trials
Missouri 2 trials
Maryland 2 trials
Illinois 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Venous Insufficiency page

10 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Venous Insufficiency condition card totals 10 registered trials; most-linked intervention Dual Action Pneumatic Compression; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.