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ClinicalTrials.gov 1 recruiting now official registry

Recurrent Malignant Germ Cell Tumor clinical trials

Every US clinical trial registered for Recurrent Malignant Germ Cell Tumor — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

8 US clinical trials · 1 currently recruiting

The research picture

Recurrent Malignant Germ Cell Tumor has 8 registered US clinical trials, 1 of them open to new participants right now — about 13% of the total.

1
recruiting participants now
13%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
7
top sponsor: National Cancer Institute (NCI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 1 90 participants

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

St. Jude Children's Research Hospital

NCT04901702

ACTIVE NOT RECRUITING Phase 2 20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03698994

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 2 9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213704

ACTIVE NOT RECRUITING Phase 2 5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04284774

ACTIVE NOT RECRUITING Phase 2 3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT04195555

ACTIVE NOT RECRUITING Phase 2 1 participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04320888

COMPLETED Phase 2 23 participants

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03526250

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Malignant Germ Cell Tumor Trial Landscape

ClinicalTrials.gov lists 8 US studies indexed under Recurrent Malignant Germ Cell Tumor, and 1 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Malignant Germ Cell Tumor shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Malignant Germ Cell Tumor is led by National Cancer Institute (NCI) with 7 indexed trials, alongside 1 other organization in the top contributor list. The list on this page surfaces up to 8 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Malignant Germ Cell Tumor?

PlainTrial tracks 8 US clinical trials for Recurrent Malignant Germ Cell Tumor, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Malignant Germ Cell Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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