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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Recurrent Malignant Germ Cell Tumor: early-phase trial registry

1 of 8 indexed Recurrent Malignant Germ Cell Tumor trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 1 currently recruiting · #2,176 of 28,707 conditions by registered trial count

Recurrent Malignant Germ Cell Tumor: 8 US clinical trials tracked, 1 recruiting.

Recurrent Malignant Germ Cell Tumor is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition recurrent-malignant-germ-cell-tumor

OPEN 1 | RECR 13% | LATE 0 | EARLY 8 | RANK #2176 | SPON 7

Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)

Activity, Motor75%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%Recurrent Malignant Germ (this)Recurrent Malignant Germ (th…13%
Open-enrollment share among volume-matched conditions near Recurrent Malignant Germ Cell Tumor

Recurrent Malignant Germ Cell Tumor lists 1 open slots (13% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Malignant Germ Cell Tumor on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Malignant Germ Cell Tumor is recruiting below its size-band peers.

    1 of 8 indexed trials (12.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Malignant Germ Cell Tumor research.

    National Cancer Institute (NCI) accounts for 7 of 8 trials (87.5%). 2 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Malignant Germ Cell Tumor trials plan to enrol fewer than 100 people.

    Median target enrolment is 13 among the 8 trials that report a genuine target (sentinel values excluded). 8 of those (100%) plan for fewer than 100 participants.

  4. Recurrent Malignant Germ Cell Tumor research is mostly interventional.

    8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 27

Open and recent trials

8 total, page 1 of 1

RECRUITING Phase 1 90 participants

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

St. Jude Children's Research Hospital

NCT04901702

ACTIVE NOT RECRUITING Phase 2 20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03698994

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 2 9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213704

ACTIVE NOT RECRUITING Phase 2 5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04284774

ACTIVE NOT RECRUITING Phase 2 3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT04195555

ACTIVE NOT RECRUITING Phase 2 1 participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04320888

COMPLETED Phase 2 23 participants

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03526250

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7

Named interventions

Most-linked intervention names on Recurrent Malignant Germ Cell Tumor records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
3 trials
Bone Marrow Aspiration and Biopsy Procedure
2 trials
Bone Scan Procedure
2 trials
Biospecimen Collection Procedure
2 trials
Radionuclide Imaging Procedure
1 trials
Pharmacological Study Other
1 trials
Ensartinib Drug
1 trials
Onivyde Drug
1 trials

US sites by state

Facility locations filed on Recurrent Malignant Germ Cell Tumor trials. A trial with sites in several states counts in each.

California 8 trials
Arizona 7 trials
Arkansas 7 trials
Alabama 7 trials
Alaska 7 trials
Colorado 5 trials
Delaware 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Malignant Germ Cell Tumor page

8 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Malignant Germ Cell Tumor condition card totals 8 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.