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ClinicalTrials.gov 6 recruiting now full pipeline small index

OSA: full-pipeline trial registry

6 of 15 indexed OSA trials are currently recruiting.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 6 currently recruiting · #1,140 of 28,707 conditions by registered trial count

OSA: 15 US clinical trials tracked, 6 recruiting.

OSA is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 2 of these trials.

Enrollment posture brief

Registry condition osa

OPEN 6 | RECR 40% | LATE 3 | EARLY 2 | RANK #1140 | SPON 2

Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)

Advanced Lung Non-Small Cell53.3%OSA (this)40%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near OSA

OSA lists 6 open slots (40% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for OSA on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. OSA is recruiting below its size-band peers.

    6 of 15 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of OSA trials is spread across many organizations.

    Brigham and Women's Hospital accounts for 2 of 15 trials (13.3%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most OSA trials plan to enrol fewer than 100 people.

    Median target enrolment is 36 among the 15 trials that report a genuine target (sentinel values excluded). 9 of those (60%) plan for fewer than 100 participants.

  4. OSA research is mostly interventional.

    12 interventional and 3 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 32Phase 41

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 1 260 participants

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

University of California, San Diego

NCT05094271

RECRUITING 60 participants

Diagnosing Obstructive Sleep Apnea Using Electromyography of the Muscles of the Mouth

University of California, San Diego

NCT06944782

RECRUITING NA 36 participants

Mandibular Advancement Device and Changes in Nocturia

Fernanda Yanez Regonesi

NCT05562388

RECRUITING Phase 1 36 participants

Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA

Brigham and Women's Hospital

NCT06091085

RECRUITING NA 36 participants

Reversible Effect of Falling Ventilatory Drive in Drive-dependent OSA

Brigham and Women's Hospital

NCT06091098

RECRUITING NA 28 participants

The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

VA Office of Research and Development

NCT05254431

ACTIVE NOT RECRUITING Phase 3 600 participants

A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Eli Lilly and Company

NCT06649045

ACTIVE NOT RECRUITING NA 150 participants

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

LivaNova

NCT04950894

COMPLETED Phase 3 660 participants

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

Apnimed

NCT05811247

COMPLETED Phase 4 250 participants

Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea

Ventus Medical

NCT00772044

COMPLETED 128 participants

Impact of OSA on Outcomes in Acute Coronary Syndrome

MetroHealth Medical Center

NCT03793582

COMPLETED NA 29 participants

Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI

VA Office of Research and Development

NCT03664765

COMPLETED NA 22 participants

Sham CPAP vs. Straight CPAP for Chronic Cough

Krishna M. Sundar

NCT03172130

COMPLETED NA 12 participants

Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea

Somnial

NCT05881512

COMPLETED 6 participants

Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea

Manhattan Beach Orthodontics

NCT04874727

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 2
Phase 4 1

Named interventions

Most-linked intervention names on OSA records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Sham exercise Other
1 trials
UA and RMT Other
1 trials
Transcutaneous Upper Airway Stimulation Device Device
1 trials
Provent Professional Sleep Apnea Therapy Device Device
1 trials
Straight CPAP Device
1 trials
ApneaLink Type III portable sleep study Diagnostic test
1 trials
Mandible slacked and captured with Correct Plus™ Impression Material Superfast Procedure
1 trials

US sites by state

Facility locations filed on OSA trials. A trial with sites in several states counts in each.

California 7 trials
Texas 3 trials
Massachusetts 3 trials
Kentucky 3 trials
Georgia 3 trials
Florida 3 trials
Arizona 3 trials
Utah 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this OSA page

15 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This OSA condition card totals 15 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.