Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 1 recruiting now official registry

Nonalcoholic Fatty Liver Disease clinical trials

1 of 10 indexed Nonalcoholic Fatty Liver Disease trials are currently recruiting.

10 US clinical trials · 1 currently recruiting

Nonalcoholic Fatty Liver Disease is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 2 of these trials.

The research picture

Nonalcoholic Fatty Liver Disease has 10 registered US clinical trials, 1 of them open to new participants right now, about 10% of the total.

1
recruiting participants now
10%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Pfizer
Phase 24Phase 31Phase 41

Active & Recent Trials

10 total, page 1 of 1

RECRUITING 30 participants

Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

West Virginia University

NCT05507151

ACTIVE NOT RECRUITING Phase 2 284 participants

Phase 2b Study of GSK4532990 in Adults With NASH

GlaxoSmithKline

NCT05583344

ACTIVE NOT RECRUITING 17 participants

Patient and Physician Perspectives on Non-Alcoholic Fatty Liver Disease

M.D. Anderson Cancer Center

NCT04132440

COMPLETED Phase 2 256 participants

Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

Pfizer

NCT04321031

COMPLETED Phase 4 176 participants

University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)

University of Florida

NCT00994682

COMPLETED Phase 2 124 participants

Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)

Merck Sharp & Dohme

NCT06482112

COMPLETED Phase 2 75 participants

Study of Pharmacodynamics and Safety of DGAT2i and ACCi Coadministered in Participants With Sponsor-defined Presumed Non Alcoholic Steatohepatitis

Pfizer

NCT04399538

COMPLETED NA 40 participants

Dietary Treatment Study of Pediatric NAFLD

University of California, San Diego

NCT02513121

COMPLETED 25 participants

Autonomic Dysfunction in Non-Alcoholic Fatty Liver Disease

Virginia Commonwealth University

NCT02132780

COMPLETED Phase 3 12 participants

Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes

University of Massachusetts, Worcester

NCT02132442

Phase Distribution

PhaseTrial count
Phase 2 4
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Nonalcoholic Fatty Liver Disease Trial Landscape

10 indexed Nonalcoholic Fatty Liver Disease studies · 1 recruiting (10%).

Phase mix: 2 late (III/IV) vs 4 early (I/II).

Top sponsor: Pfizer (2 trials), 8 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Nonalcoholic Fatty Liver Disease?

PlainTrial tracks 10 US clinical trials for Nonalcoholic Fatty Liver Disease, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Nonalcoholic Fatty Liver Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.