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Colo-rectal Cancer clinical trials
8 of 12 indexed Colo-rectal Cancer trials are currently recruiting.
12 US clinical trials · 8 currently recruiting
Colo-rectal Cancer is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Roswell Park Cancer Institute, running 2 of these trials.
The research picture
Colo-rectal Cancer has 12 registered US clinical trials, 8 of them open to new participants right now, about 67% of the total.
- 8
- recruiting participants now
- 67%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Roswell Park Cancer Institute
Active & Recent Trials
12 total, page 1 of 1
Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)
Natera
NCT07046585
Shield Post-Approval Study Protocol
Guardant Health
NCT06880055
Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
Roswell Park Cancer Institute
NCT06563388
A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
ALX Oncology
NCT07085091
Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
MBrace Therapeutics
NCT07145255
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients
Vyriad
NCT04291105
Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery
University of California, Davis
NCT05321134
Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
Massachusetts General Hospital
NCT05524428
A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors
NextCure
NCT05572684
EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer
Roswell Park Cancer Institute
NCT06011772
Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.
Exact Sciences Corporation
NCT03741166
Understanding Patient Preference on Colorectal Cancer Screening Options-PSU
Milton S. Hershey Medical Center
NCT06444542
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Colo-rectal Cancer Trial Landscape
12 indexed Colo-rectal Cancer studies · 8 recruiting (67%).
Phase mix: 1 late (III/IV) vs 5 early (I/II).
Top sponsor: Roswell Park Cancer Institute (2 trials), 9 others listed. 12 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Colo-rectal Cancer?
PlainTrial tracks 12 US clinical trials for Colo-rectal Cancer, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Colo-rectal Cancer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.