Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Stage IV Esophageal Adenocarcinoma 1
Stage IV Esophageal Adenocarcinoma AJCC v7 1
Stage IV Esophageal Cancer 2
Stage IV Esophageal Cancer AJCC v7 2
Stage IV Esophageal Squamous Cell Carcinoma 1
Stage IV Fallopian Tube Cancer 1
Stage IV Fallopian Tube Cancer AJCC v6 and v7 1
Stage IV Fallopian Tube Cancer AJCC v8 4
Stage IV Follicular Lymphoma 1
Stage IV Gallbladder Cancer AJCC v7 1
Stage IV Gallbladder Cancer AJCC v8 2
Stage IV Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8 1
Stage IV Gastric Cancer 6
Stage IV Gastric Cancer AJCC v7 1
Stage IV Gastrointestinal Cancer 1
Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma 1
Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 1
Stage IV Hepatocellular Carcinoma 1
Stage IV Hepatocellular Carcinoma AJCC v8 15
Stage IV High Grade B-Cell Lymphoma 1
Stage IV Hilar Cholangiocarcinoma AJCC v8 1
Stage IV Hypopharyngeal Carcinoma AJCC v8 1
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 3
Stage IV Inflammatory Breast Carcinoma 1
Stage IV Intrahepatic Bile Duct Cancer AJCC v8 1
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 9
Stage IV Kidney Wilms Tumor 3
Stage IV Laryngeal Cancer AJCC v8 1
Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7 3
Stage IV Lip and Oral Cavity Cancer AJCC v8 1
Stage IV Liver Cancer 2
Stage IV Lung Adenocarcinoma 1
Stage IV Lung Cancer 6
Stage IV Lung Cancer AJCC v8 82
Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8 1
Stage IV Lung Non-Small Cell Cancer AJCC v7 8
Stage IV Major Salivary Gland Cancer AJCC v7 1
Stage IV Major Salivary Gland Cancer AJCC v8 3
Stage IV Malignant Melanoma 1
Stage IV Malignant Mesothelioma 1
Stage IV Melanoma 15
Stage IV Merkel Cell Carcinoma AJCC v7 1
Stage IV Mixed Cell Type Kidney Wilms Tumor 1
Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8 2
Stage IV Nasopharyngeal Cancer 1
Stage IV Nasopharyngeal Carcinoma AJCC v8 3
Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 2
Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7 2
Stage IV Non-small Cell Lung Cancer 24
Stage IV Non-Small Cell Lung Cancer AJCC v7 3