Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Stage IIIC1 Cervical Cancer FIGO 2018 1
Stage IIIC1 Uterine Corpus Cancer AJCC v8 1
Stage IIIC2 Cervical Cancer FIGO 2018 1
Stage IIIC2 Uterine Corpus Cancer AJCC v8 1
Stage IS Testicular Cancer AJCC v8 1
Stage IV A Bladder Cancer 1
Stage IV A Rectal Cancer 1
Stage IV Adenocarcinoma of the Gastroesophageal Junction 1
Stage IV Adrenal Cortex Carcinoma AJCC v8 2
Stage IV Adrenal Cortical Carcinoma AJCC v8 1
Stage IV Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8 1
Stage IV Adult Soft Tissue Sarcoma 7
Stage IV Adult Soft Tissue Sarcoma AJCC v7 1
Stage IV Anal Cancer AJCC v8 2
Stage IV Angioimmunoblastic T-cell Lymphoma 1
Stage IV B Colon Cancer 1
Stage IV B Rectal Cancer 1
Stage IV Bladder Cancer 4
Stage IV Bladder Cancer AJCC v7 2
Stage IV Bladder Cancer AJCC v8 8
Stage IV Bladder Urothelial Carcinoma 1
Stage IV Bladder Urothelial Carcinoma AJCC v7 6
Stage IV Breast Cancer 31
Stage IV Breast Cancer AJCC v6 and v7 15
Stage IV Breast Cancer AJCC V7 1
Stage IV Breast Inflammatory Carcinoma 1
Stage IV Cervical Cancer AJCC v6 and v7 2
Stage IV Cervical Cancer AJCC v8 2
Stage IV Cervical Cancer FIGO 2018 1
Stage IV Childhood Hepatocellular Carcinoma 1
Stage IV Childhood Hodgkin Lymphoma 1
Stage IV Choroidal and Ciliary Body Melanoma AJCC V8 1
Stage IV Chronic Lymphocytic Leukemia 3
Stage IV Colon Cancer 7
Stage IV Colon Cancer AJCC v7 1
Stage IV Colon Cancer AJCC v8 3
Stage IV Colon Cancer With Resectable Liver Metastases 1
Stage IV Colorectal Cancer 2
Stage IV Colorectal Cancer AJCC v7 8
Stage IV Colorectal Cancer AJCC v8 23
Stage IV Colorectal Cancer Positive for BRAF V600E Mutation 1
Stage IV Cutaneous Melanoma 2
Stage IV Cutaneous Melanoma AJCC v6 and v7 18
Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck 2
Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 2
Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8 1
Stage IV Diffuse Large B-Cell Lymphoma 1
Stage IV Distal Bile Duct Cancer AJCC v8 2
Stage IV Endometrial Cancer 1
Stage IV Enteropathy-Associated T-Cell Lymphoma 1