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NCT07693270 · ClinicalTrials.gov registry record
Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery
A clinical trial, sponsored by University of California, San Diego.
- Not yet
- Registry status
- 100
- Enrollment target
NCT07693270 is a clinical trial that has not yet begun recruiting, run by University of California, San Diego. The registered enrollment target is 100 participants.
The verdict
NCT07693270 has not yet begun recruiting, sponsored by University of California, San Diego.
- NOT YET RECRUITING
- Registry status
- 100 participants
- Enrollment target
Study Summary
The mechanisms leading to opioid tolerance or dependence are not well understood and there are currently no biomarkers for predicting who is at risk for development of OUD. The purpose of this project is to support the feasibility of detecting a miRNA bio-behavioral signature of opioid misuse risk that will demonstrate improved predictive precision compared to current tools such as polygenic risk scores (PRS). Specifically, the study will address key goals of the Wellcome Leap program to develop scalable measures assessing individual addiction susceptibility and quantifying addiction risk and progression during prescription drug use. The study will utilize behavioral, genomics, and bioinformatics pipelines to characterize opioid-induced miRNA expression dynamics among trauma and surgical patients prescribed opioids at discharge. Based on results from this study, the research will develop a high-throughput screening assay to predict risk for opioid use disorder (OUD). The hypothesis is that miRNAs will serve as powerful bio-signatures for predicting long-term clinical outcomes in patients treated with opioids for pain management following trauma injury and/or surgery.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-07 |
| Est. Completion | 2027-06 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07693270
The ClinicalTrials.gov registry entry for NCT07693270 describes a study currently listed as not yet recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT07693270 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07693270 about?
NCT07693270 is a clinical study titled "Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery". The mechanisms leading to opioid tolerance or dependence are not well understood and there are currently no biomarkers for predicting who is at risk for development of OUD. The purpose of this project is to support the feasibility of detecting a miRNA bio-behavioral signature of opioid misuse risk t...
What is the current status of trial NCT07693270?
This trial is currently not yet recruiting. The enrollment target is 100 participants. The study started on 2026-07. Estimated completion is 2027-06.
Who is sponsoring clinical trial NCT07693270?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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