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NCT07693205 · ClinicalTrials.gov registry record · Phase 4

A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects

A Phase 4 study, sponsored by Berkeley Eye Center.

Recruiting
Registry status
Phase 4
Development phase
180
Enrollment target

NCT07693205: Recruiting Phase 4 study, sponsored by Berkeley Eye Center.

NCT07693205 is a Phase 4 study that is actively recruiting participants, run by Berkeley Eye Center. The registered enrollment target is 180 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07693205, a Phase 4 study, is actively recruiting participants, sponsored by Berkeley Eye Center.

RECRUITING
Registry status
Phase 4
Development phase
180 participants
Enrollment target

Study Summary

This investigator-initiated trial is a prospective, randomized, parallel-group, bilateral implantation study comparing Clareon TruPlus versus Clareon monofocal intraocular lenses (IOLs). Spherical and toric models are permitted in both arms based on standardized preoperative planning and clinical indication. Subjects and postoperative examiners/technicians will be masked to IOL assignment; surgeons will not be masked. The overall structure is modeled after randomized bilateral implantation cataract study designs with a Month 3 primary endpoint visit.

Interventions

  • DEVICE Clareon TruPlus
  • DEVICE Clareon monofocal

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2026-07
Est. Completion 2027-07
Phase Phase 4
Berkeley Eye Center

8 total trials

What NCT07693205 shows while recruiting

NCT07693205 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 2 interventions - of which Clareon TruPlus is the first listed.

NCT07693205 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07693205 about?

NCT07693205 is a clinical study titled "A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects". This investigator-initiated trial is a prospective, randomized, parallel-group, bilateral implantation study comparing Clareon TruPlus versus Clareon monofocal intraocular lenses (IOLs). Spherical and toric models are permitted in both arms based on standardized preoperative planning and clinical in...

What is the current status of trial NCT07693205?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 180 participants. The study started on 2026-07. Estimated completion is 2027-07.

What interventions are being tested in trial NCT07693205?

The interventions under investigation include: Clareon TruPlus (DEVICE), Clareon monofocal (DEVICE).

Who is sponsoring clinical trial NCT07693205?

This trial is sponsored by Berkeley Eye Center, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07693205's enrollment target sits among peer trials

180 466th of 2000 higher than 1,525 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07693205, the US trial registry maintained by the National Library of Medicine. NCT07693205 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.