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NCT07680114 · ClinicalTrials.gov registry record · NA
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
A NA study, sponsored by University of Wisconsin, Madison.
- Not yet
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT07680114: Clinical Trial NA study, sponsored by University of Wisconsin, Madison.
NCT07680114 is a NA study that has not yet begun recruiting, run by University of Wisconsin, Madison. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07680114, a NA study, has not yet begun recruiting, sponsored by University of Wisconsin, Madison.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep spindles (brain rhythms in the \~8-16 Hz range). The investigators are focusing on the thalamus, a deep brain region that helps coordinate brain activity during non-REM sleep. Sleep spindles are often reduced in schizophrenia, so this study is to see whether TES-TI can change spindle activity in individuals with schizophrenia spectrum disorders (SSD) and in healthy adults. To study this, a structural MRI scan will be used to customize where the stimulation electrodes are placed, and then TES-TI will be applied during one of two overnight sleep lab visits while brain activity is recorded with high-density EEG and standard sleep sensors. The other overnight is a baseline/control night during which only sham stimulation is delivered. The goal is to determine whether TES-TI during sleep can increase spindle-frequency activity in this population.
Interventions
- DEVICE TES-TI
- DEVICE Sham TES-TI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-08 |
| Est. Completion | 2027-12 |
| Phase | NA |
What is known before NCT07680114 opens enrollment
NCT07680114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which TES-TI is the first listed.
NCT07680114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07680114 about?
NCT07680114 is a clinical study titled "Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls". This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep spindles (brain rhythms in the \~8-16 Hz range). The investigators are...
What is the current status of trial NCT07680114?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-08. Estimated completion is 2027-12.
What interventions are being tested in trial NCT07680114?
The interventions under investigation include: TES-TI (DEVICE), Sham TES-TI (DEVICE).
Who is sponsoring clinical trial NCT07680114?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07680114's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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