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NCT07680114 · ClinicalTrials.gov registry record · NA

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

A NA study, sponsored by University of Wisconsin, Madison.

Not yet
Registry status
NA
Development phase
20
Enrollment target

NCT07680114 is a NA study that has not yet begun recruiting, run by University of Wisconsin, Madison. The registered enrollment target is 20 participants.

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The verdict

NCT07680114, a NA study, has not yet begun recruiting, sponsored by University of Wisconsin, Madison.

NOT YET RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep spindles (brain rhythms in the \~8-16 Hz range). The investigators are focusing on the thalamus, a deep brain region that helps coordinate brain activity during non-REM sleep. Sleep spindles are often reduced in schizophrenia, so this study is to see whether TES-TI can change spindle activity in individuals with schizophrenia spectrum disorders (SSD) and in healthy adults. To study this, a structural MRI scan will be used to customize where the stimulation electrodes are placed, and then TES-TI will be applied during one of two overnight sleep lab visits while brain activity is recorded with high-density EEG and standard sleep sensors. The other overnight is a baseline/control night during which only sham stimulation is delivered. The goal is to determine whether TES-TI during sleep can increase spindle-frequency activity in this population.

Interventions

  • DEVICE TES-TI
  • DEVICE Sham TES-TI

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-08
Est. Completion 2027-12
Phase NA

Sponsor

University of Wisconsin, Madison

1,039 total trials

What the Registry Record Tells You About NCT07680114

The ClinicalTrials.gov registry entry for NCT07680114 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which TES-TI is the first listed.

NCT07680114 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07680114 about?

NCT07680114 is a clinical study titled "Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls". This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep spindles (brain rhythms in the \~8-16 Hz range). The investigators are...

What is the current status of trial NCT07680114?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-08. Estimated completion is 2027-12.

What interventions are being tested in trial NCT07680114?

The interventions under investigation include: TES-TI (DEVICE), Sham TES-TI (DEVICE).

Who is sponsoring clinical trial NCT07680114?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.