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NCT07668882 · ClinicalTrials.gov registry record · NA
Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering
A NA study, sponsored by University of Michigan.
- Not yet
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT07668882: Clinical Trial NA study, sponsored by University of Michigan.
NCT07668882 is a NA study that has not yet begun recruiting, run by University of Michigan. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07668882, a NA study, has not yet begun recruiting, sponsored by University of Michigan.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
This research is studying the use of low-intensity focused ultrasound (LIFU; a mild, noninvasive acoustic stimulation technique) in a small number of people to learn about its safety as a treatment for stuttering. LIFU is a small, safe sound signal that produces a gentle, pulsing flow of acoustic waves to help different parts of the brain communicate with each other. Researchers want to understand how the mild, non-invasive brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people who stutter.
Primary Outcome
The study will calculate the percentage of stuttered syllables (out of total syllables) in two speech samples (one before LIFU and one sample after LIFU) per each stimulation session. Decreased stuttered syllables represents better outcomes (greater reduction in stuttering). Two samples are collected during session 1 and two samples are collected during session 2. An additional baseline sample is collected at the baseline session (on a separate day before the two stimulation sessions).
Interventions
- DEVICE Sham
- DEVICE High DC LIFU
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-06 |
| Est. Completion | 2027-06 |
| Phase | NA |
What is known before NCT07668882 opens enrollment
NCT07668882 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.
NCT07668882 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07668882 about?
NCT07668882 is a clinical study titled "Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering". This research is studying the use of low-intensity focused ultrasound (LIFU; a mild, noninvasive acoustic stimulation technique) in a small number of people to learn about its safety as a treatment for stuttering. LIFU is a small, safe sound signal that produces a gentle, pulsing flow of acoustic wa...
What is the current status of trial NCT07668882?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-06. Estimated completion is 2027-06.
What interventions are being tested in trial NCT07668882?
The interventions under investigation include: Sham (DEVICE), High DC LIFU (DEVICE).
Who is sponsoring clinical trial NCT07668882?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07668882's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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