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NCT07643766 · ClinicalTrials.gov registry record · Phase 2

A Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

A Phase 2 study, sponsored by Enveda Therapeutics.

Not yet
Registry status
Phase 2
Development phase
200
Enrollment target

NCT07643766: Clinical Trial Phase 2 study, sponsored by Enveda Therapeutics.

NCT07643766 is a Phase 2 study that has not yet begun recruiting, run by Enveda Therapeutics. The registered enrollment target is 200 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07643766, a Phase 2 study, has not yet begun recruiting, sponsored by Enveda Therapeutics.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
200 participants
Enrollment target

Study Summary

This double-blind, placebo-controlled study is designed to evaluate the safety and efficacy of ENV-294 in adults with moderate-to-severe atopic dermatitis (AD). The study will compare three dose levels of ENV-294 with placebo administered for 12 weeks. Participants will undergo screening, receive study treatment, and complete scheduled assessments of disease activity, symptoms, quality of life, safety, pharmacokinetics, and biomarker responses.

Interventions

  • OTHER Placebo
  • DRUG ENV-294

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2026-06
Est. Completion 2028-05
Phase Phase 2
Enveda Therapeutics

4 total trials

What is known before NCT07643766 opens enrollment

NCT07643766 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07643766 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07643766 about?

NCT07643766 is a clinical study titled "A Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis". This double-blind, placebo-controlled study is designed to evaluate the safety and efficacy of ENV-294 in adults with moderate-to-severe atopic dermatitis (AD). The study will compare three dose levels of ENV-294 with placebo administered for 12 weeks. Participants will undergo screening, receive st...

What is the current status of trial NCT07643766?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2026-06. Estimated completion is 2028-05.

What interventions are being tested in trial NCT07643766?

The interventions under investigation include: Placebo (OTHER), ENV-294 (DRUG).

Who is sponsoring clinical trial NCT07643766?

This trial is sponsored by Enveda Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07643766's enrollment target sits among peer trials

200 304th of 2000 higher than 1,652 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07643766, the US trial registry maintained by the National Library of Medicine. NCT07643766 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.