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NCT07643467 · ClinicalTrials.gov registry record · Phase 4

Fluorescent Probe for Assessment of Renal Elimination

A Phase 4 study, sponsored by Aaron Cook.

Not yet
Registry status
Phase 4
Development phase
200
Enrollment target

NCT07643467: Clinical Trial Phase 4 study, sponsored by Aaron Cook.

NCT07643467 is a Phase 4 study that has not yet begun recruiting, run by Aaron Cook. The registered enrollment target is 200 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07643467, a Phase 4 study, has not yet begun recruiting, sponsored by Aaron Cook.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
200 participants
Enrollment target

Study Summary

Accurate measures of kidney function is important for precision dosing of many medications. The current methods of determining kidney function largely hinge on the use of equations that use common laboratory values such as serum creatinine \& static variables like age \& weight. These are helpful for trending over time, but often are inaccurate during times of medical illness. Other more accurate methods of measuring kidney function include urine collection, although this is not commonly used because of various reasons that make the collection inconvenient or unreliable. The new transdermal glomerular filtration (tGFR) device permits accurate, real-time evaluation of kidney function. This novel method has not been rigorously compared with urine collection \& other methods of determining kidney function in hospitalized patients. The goal of the study is to compare tGFR with other accepted methods of determining kidney function.

Primary Outcome

Accuracy of transdermal glomerular filtration rate (GFR) monitoring compared with measured urine creatinine clearance.

Interventions

  • DRUG Iohexol
  • DRUG Relmapirazin
  • DEVICE Medibeacon tGFR monitor
  • DIAGNOSTIC_TEST Urine creatinine clearance collection

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2026-07
Est. Completion 2028-06-30
Phase Phase 4
Aaron Cook

3 total trials

What is known before NCT07643467 opens enrollment

NCT07643467 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (61% lower).

The record links to 0 conditions, and to 4 interventions - of which Iohexol is the first listed.

NCT07643467 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07643467 about?

NCT07643467 is a clinical study titled "Fluorescent Probe for Assessment of Renal Elimination". Accurate measures of kidney function is important for precision dosing of many medications. The current methods of determining kidney function largely hinge on the use of equations that use common laboratory values such as serum creatinine \& static variables like age \& weight. These are helpful fo...

What is the current status of trial NCT07643467?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 200 participants. The study started on 2026-07. Estimated completion is 2028-06-30.

What interventions are being tested in trial NCT07643467?

The interventions under investigation include: Iohexol (DRUG), Relmapirazin (DRUG), Medibeacon tGFR monitor (DEVICE), Urine creatinine clearance collection (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT07643467?

This trial is sponsored by Aaron Cook, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07643467's enrollment target sits among peer trials

200 407th of 2000 higher than 1,556 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07643467, the US trial registry maintained by the National Library of Medicine. NCT07643467 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.