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NCT07635940 · ClinicalTrials.gov registry record · NA
Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture
A NA study, sponsored by University of Colorado, Denver.
- Not yet
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT07635940: Clinical Trial NA study, sponsored by University of Colorado, Denver.
NCT07635940 is a NA study that has not yet begun recruiting, run by University of Colorado, Denver. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07635940, a NA study, has not yet begun recruiting, sponsored by University of Colorado, Denver.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated psychopathic traits. The study will also evaluate the safety and feasibility of delivering TMS in this population. Participants will be randomly assigned to receive either active TMS or sham (placebo-like) TMS. The study will compare outcomes between participants receiving active versus sham TMS and will evaluate changes from before to after TMS exposure. Participants will: * Complete a baseline magnetic resonance imaging (MRI) brain scan. * Receive three single-session TMS interventions. * Complete a post-intervention MRI brain scan. * Complete assessments of social cognition. * Complete assessments of cognitive processing. The primary objectives are to determine whether TMS can influence social cognition, cognitive processing, and functional brain organization and connectivity in adults with elevated psychopathic traits.
Primary Outcome
Performance on a social cognition task battery assessing facial emotion recognition (Emotion Recognition Task), perspective taking (Visual Perspective Taking Task), theory of mind (Movie Assessment of Social Cognition Task), and social decision-making (Altruistic/Antisocial game). Accuracy and reaction time will be analyzed using mixed-effects models to compare active stimulation versus sham stimulation across tasks. Higher accuracy values indicate better performance, whereas lower reaction time
Interventions
- DEVICE continuous theta burst stimulation (cTBS)
- DEVICE Sham
- DEVICE Intermittent theta burst stimulation (iTBS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-06 |
| Est. Completion | 2030-08 |
| Phase | NA |
What is known before NCT07635940 opens enrollment
NCT07635940 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 3 interventions - of which continuous theta burst stimulation (cTBS) is the first listed.
NCT07635940 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07635940 about?
NCT07635940 is a clinical study titled "Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture". This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated psychopathic traits. The study will also evaluate the safety and feasibility of ...
What is the current status of trial NCT07635940?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2026-06. Estimated completion is 2030-08.
What interventions are being tested in trial NCT07635940?
The interventions under investigation include: continuous theta burst stimulation (cTBS) (DEVICE), Sham (DEVICE), Intermittent theta burst stimulation (iTBS) (DEVICE).
Who is sponsoring clinical trial NCT07635940?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07635940's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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