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NCT07631299 · ClinicalTrials.gov registry record · Early Phase 1
Nebulized AER101 in Pre-op NSCLC
A Early Phase 1 study, sponsored by University of Oklahoma.
- Not yet
- Registry status
- Early Phase 1
- Development phase
- 5
- Enrollment target
NCT07631299: Clinical Trial Early Phase 1 study, sponsored by University of Oklahoma.
NCT07631299 is a Early Phase 1 study that has not yet begun recruiting, run by University of Oklahoma. The registered enrollment target is 5 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07631299, a Early Phase 1 study, has not yet begun recruiting, sponsored by University of Oklahoma.
- NOT YET RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The primary objective of this pilot study is to determine if AER101 can decrease glycolysis in non-small cell lung cancer (NSCLC). Glycolysis is the process cells use to break down sugar (glucose) into a smaller substance in the fluid part inside the cell. Many lung cancers begin in bronchi, bronchioles and alveoli cells surrounding the airways, which enables nebulization to deposit AER101 on lung tumors. Participants in the study will self-administer AER101 via a hand-held personal nebulizer three times per day (dosing at least 4 hours apart) for 14 days prior to undergoing surgery for lung cancer.
Primary Outcome
decreased glycolysis
Interventions
- DRUG AER101
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2026-06 |
| Est. Completion | 2027-06 |
| Phase | Early Phase 1 |
What is known before NCT07631299 opens enrollment
NCT07631299 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which AER101 is the first listed.
NCT07631299 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07631299 about?
NCT07631299 is a clinical study titled "Nebulized AER101 in Pre-op NSCLC". The primary objective of this pilot study is to determine if AER101 can decrease glycolysis in non-small cell lung cancer (NSCLC). Glycolysis is the process cells use to break down sugar (glucose) into a smaller substance in the fluid part inside the cell. Many lung cancers begin in bronchi, bronchi...
What is the current status of trial NCT07631299?
This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2026-06. Estimated completion is 2027-06.
What interventions are being tested in trial NCT07631299?
The interventions under investigation include: AER101 (DRUG).
Who is sponsoring clinical trial NCT07631299?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07631299's enrollment target sits among peer trials
5 1887th of 2000 higher than 80 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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