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NCT07629765 · ClinicalTrials.gov registry record · NA
Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study
A NA study, sponsored by Edward Via Virginia College of Osteopathic Medicine.
- Not yet
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT07629765: Clinical Trial NA study, sponsored by Edward Via Virginia College of Osteopathic Medicine.
NCT07629765 is a NA study that has not yet begun recruiting, run by Edward Via Virginia College of Osteopathic Medicine. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07629765, a NA study, has not yet begun recruiting, sponsored by Edward Via Virginia College of Osteopathic Medicine.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
his study aims to investigate whether Osteopathic Manipulative Treatment (OMT) affects cerebrospinal fluid (CSF) flow and glymphatic clearance in the human brain. CSF plays an important role in brain health by supporting nutrient delivery, waste removal, and pressure regulation. Aging and certain neurological conditions are associated with reduced CSF circulation and impaired brain waste clearance. Participants will undergo magnetic resonance imaging (MRI) scans before and after a 30-minute OMT session to evaluate changes in CSF flow dynamics and brain physiology. The study will also examine whether age, cognition, sleep quality, physical function, anxiety, and depression are associated with changes in CSF flow following OMT. The study will enroll healthy adults between 18 and 80 years of age. Data collected from MRI imaging and questionnaires may help improve understanding of the physiological effects of OMT and its potential role in supporting brain health
Primary Outcome
CSF aqueductal peak and average velocity measured using phase contrast MRI before and after osteopathic manipulative treatment (OMT).
Interventions
- OTHER Osteopathic Manipulative Treatment (OMT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2026-06 |
| Est. Completion | 2027-08 |
| Phase | NA |
What is known before NCT07629765 opens enrollment
NCT07629765 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Osteopathic Manipulative Treatment (OMT) is the first listed.
NCT07629765 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07629765 about?
NCT07629765 is a clinical study titled "Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study". his study aims to investigate whether Osteopathic Manipulative Treatment (OMT) affects cerebrospinal fluid (CSF) flow and glymphatic clearance in the human brain. CSF plays an important role in brain health by supporting nutrient delivery, waste removal, and pressure regulation. Aging and certain ne...
What is the current status of trial NCT07629765?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2026-06. Estimated completion is 2027-08.
What interventions are being tested in trial NCT07629765?
The interventions under investigation include: Osteopathic Manipulative Treatment (OMT) (OTHER).
Who is sponsoring clinical trial NCT07629765?
This trial is sponsored by Edward Via Virginia College of Osteopathic Medicine, which has 19 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07629765's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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