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NCT07584681 · ClinicalTrials.gov registry record · NA
Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory
A NA study, sponsored by Northwell Health.
- Not yet
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT07584681: Clinical Trial NA study, sponsored by Northwell Health.
NCT07584681 is a NA study that has not yet begun recruiting, run by Northwell Health. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07584681, a NA study, has not yet begun recruiting, sponsored by Northwell Health.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
This study seeks to use safe, powerful, non-invasive computing tools, including machine learning and advanced neuroimaging analysis, to better understand how stroke affects the brain's network of connections. Using structural MRI, including diffusion-weighted imaging, this study will generate a detailed map of brain pathways to evaluate how strokes in the middle cerebral artery (MCA) territory disrupt the brain's structural networks. In the future, this approach may help physicians better predict recovery, monitor neuroplasticity, and guide rehabilitation decisions after stroke.
Primary Outcome
Structural and functional connectomics will be used as a metric to quantify white matter tract disruption in patients with acute ischemic stroke involving the M1 or more distal branches of the middle cerebral artery (MCA), who undergo mechanical thrombectomy and/or receive intravenous thrombolytics (Tenecteplase or Alteplase) and have persistent motor deficits after therapy. White matter tract disruption, connection density, and connection strength will be measured and quanitifed at baseline, 1
Interventions
- OTHER MRI with connectomic sequencing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-05 |
| Est. Completion | 2028-04 |
| Phase | NA |
What is known before NCT07584681 opens enrollment
NCT07584681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which MRI with connectomic sequencing is the first listed.
NCT07584681 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07584681 about?
NCT07584681 is a clinical study titled "Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory". This study seeks to use safe, powerful, non-invasive computing tools, including machine learning and advanced neuroimaging analysis, to better understand how stroke affects the brain's network of connections. Using structural MRI, including diffusion-weighted imaging, this study will generate a deta...
What is the current status of trial NCT07584681?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2026-05. Estimated completion is 2028-04.
What interventions are being tested in trial NCT07584681?
The interventions under investigation include: MRI with connectomic sequencing (OTHER).
Who is sponsoring clinical trial NCT07584681?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07584681's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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