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NCT07572383 · ClinicalTrials.gov registry record · Phase 2

Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis

A Phase 2 study, sponsored by Peter Caravan.

Recruiting
Registry status
Phase 2
Development phase
15
Enrollment target

NCT07572383: Recruiting Phase 2 study, sponsored by Peter Caravan.

NCT07572383 is a Phase 2 study that is actively recruiting participants, run by Peter Caravan. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07572383, a Phase 2 study, is actively recruiting participants, sponsored by Peter Caravan.

RECRUITING
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

The purpose of this study is to investigate how immunosuppression treatment affects measurements of active collagen deposition using \[68Ga\]CBP8 positron emission tomography (PET) and tissue injury using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in individuals with non-idiopathic pulmonary fibrosis interstitial lung disease (non-IPF ILD).

Primary Outcome

Changes in lung collagen uptake will be measured using the PET probe \[68\]Ga-CBP8. Measurements will be made using the mean of the upper quartile of standardized uptake values (SUVmax25). Primary \[68Ga\]CBP8-PET outcome.

Interventions

  • DRUG [68Ga]CBP8
  • DRUG Gadoterate Meglumine

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2026-04
Est. Completion 2028-12-31
Phase Phase 2
Peter Caravan

3 total trials

What NCT07572383 shows while recruiting

NCT07572383 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 2 interventions - of which [68Ga]CBP8 is the first listed.

NCT07572383 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07572383 about?

NCT07572383 is a clinical study titled "Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis". The purpose of this study is to investigate how immunosuppression treatment affects measurements of active collagen deposition using \[68Ga\]CBP8 positron emission tomography (PET) and tissue injury using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in individuals with non-idiopath...

What is the current status of trial NCT07572383?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2026-04. Estimated completion is 2028-12-31.

What interventions are being tested in trial NCT07572383?

The interventions under investigation include: [68Ga]CBP8 (DRUG), Gadoterate Meglumine (DRUG).

Who is sponsoring clinical trial NCT07572383?

This trial is sponsored by Peter Caravan, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07572383's enrollment target sits among peer trials

15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07572383, the US trial registry maintained by the National Library of Medicine. NCT07572383 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.