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NCT07537764 · ClinicalTrials.gov registry record · Early Phase 1
Predictors & Mechanisms of Adolescent PTSD
A Early Phase 1 study, sponsored by Medical University of South Carolina.
- Not yet
- Registry status
- Early Phase 1
- Development phase
- 180
- Enrollment target
NCT07537764 is a Early Phase 1 study that has not yet begun recruiting, run by Medical University of South Carolina. The registered enrollment target is 180 participants.
The verdict
NCT07537764, a Early Phase 1 study, has not yet begun recruiting, sponsored by Medical University of South Carolina.
- NOT YET RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 180 participants
- Enrollment target
Study Summary
This study examines how adolescents with trauma-related symptoms respond to stress and strong emotions. The study assesses brain activity, physiological responses, and behavior during experimental tasks that involve responding to potential threats, regulating emotions, and repeatedly imagining details of a personally experienced stressful or traumatic event using a script-driven imagery task. The study evaluates whether repeated imaginal exposure is associated with changes in anxiety and physiological responses across sessions, and whether baseline patterns of threat reactivity and emotion regulation are associated with individual differences in response to the exposure task. Outcomes include self-reported anxiety, subjective distress ratings, and psychophysiological indices such as heart rate, skin conductance, and electromyographic activity. The goal of this research is to improve understanding of biobehavioral processes related to trauma exposure in adolescents and to identify potential predictors of response to exposure-based intervention components relevant to posttraumatic stress disorder (PTSD).
Interventions
- BEHAVIORAL Repeated imaginal exposure: Script Driven Imagery (SDI) task
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2026-09 |
| Est. Completion | 2031-03 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07537764
The ClinicalTrials.gov registry entry for NCT07537764 describes a study currently listed as not yet recruiting, categorized as Early Phase 1. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Repeated imaginal exposure: Script Driven Imagery (SDI) task is the first listed.
NCT07537764 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07537764 about?
NCT07537764 is a clinical study titled "Predictors & Mechanisms of Adolescent PTSD". This study examines how adolescents with trauma-related symptoms respond to stress and strong emotions. The study assesses brain activity, physiological responses, and behavior during experimental tasks that involve responding to potential threats, regulating emotions, and repeatedly imagining detai...
What is the current status of trial NCT07537764?
This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 180 participants. The study started on 2026-09. Estimated completion is 2031-03.
What interventions are being tested in trial NCT07537764?
The interventions under investigation include: Repeated imaginal exposure: Script Driven Imagery (SDI) task (BEHAVIORAL).
Who is sponsoring clinical trial NCT07537764?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
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