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NCT07537153 · ClinicalTrials.gov registry record · NA
Genicular Artery Embolization for Knee Osteoarthritis
A NA study, sponsored by Northwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT07537153: Recruiting NA study, sponsored by Northwestern University.
NCT07537153 is a NA study that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07537153, a NA study, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Patients will be asked to take part in this research study because they have mild-to-moderate knee osteoarthritis (OA) and were referred clinically for a procedure called Genicular Artery Embolization (GAE). Osteoarthritis is the most common form of arthritis. It occurs when the protective cartilage that cushions the ends of the bones wears down over time. The symptoms of OA include pain or aching, stiffness, decreased range of motion, and swelling. The purpose of this study is to evaluate the safety and effectiveness of GAE for the treatment of knee pain attributed to OA. Research participants will be in this research study for about 3 years. The study includes a screening visit, GAE procedure, and six follow-up visits. At the screening visit, a review of their medical history, demographics, and medications will be collected; physical examination will be completed; knee x-ray will be done; and two questionnaires on your knee pain will be administered. The GAE procedure will involve receiving sedation or medication to help them relax, lidocaine injected under the skin in the area of the body where catheters will be inserted into one of your arteries and then using x-ray, a catheter will be directed to the arteries supplying the lining of the knee. Then tiny microspheres will be injected into the artery to decrease the blood supply to this knee joint tissue. The follow-up visits up to 12 months will include a focused physical examination of the treated knee, documentation of medications, and two questionnaires will be administered. The follow-up visits at year 2 and 3 will include documentation of medications and any new treatments for OA as well as completion of two questionnaires. Follow-up visits maybe conducted in clinic or remotely.
Primary Outcome
Primary safety endpoints include: 1\. Incidence and severity of adverse events (AEs). These include: 1. Non-target embolization (e.g., distal leg) 2. All transient intra- and post-procedure events (e.g., skin changes) 3. Death
Interventions
- DEVICE Embosphere Microspheres
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-05 |
| Est. Completion | 2031-04-10 |
| Phase | NA |
What NCT07537153 shows while recruiting
NCT07537153 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Embosphere Microspheres is the first listed.
NCT07537153 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07537153 about?
NCT07537153 is a clinical study titled "Genicular Artery Embolization for Knee Osteoarthritis". Patients will be asked to take part in this research study because they have mild-to-moderate knee osteoarthritis (OA) and were referred clinically for a procedure called Genicular Artery Embolization (GAE). Osteoarthritis is the most common form of arthritis. It occurs when the protective cartilage...
What is the current status of trial NCT07537153?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2026-05. Estimated completion is 2031-04-10.
What interventions are being tested in trial NCT07537153?
The interventions under investigation include: Embosphere Microspheres (DEVICE).
Who is sponsoring clinical trial NCT07537153?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07537153's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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