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NCT07536399 · ClinicalTrials.gov registry record · Phase 3
Biologic Augmentation of TMJ Arthroscopy Using BMAC
A Phase 3 study, sponsored by Weill Medical College of Cornell University.
- Not yet
- Registry status
- Phase 3
- Development phase
- 20
- Enrollment target
NCT07536399: Clinical Trial Phase 3 study, sponsored by Weill Medical College of Cornell University.
NCT07536399 is a Phase 3 study that has not yet begun recruiting, run by Weill Medical College of Cornell University. The registered enrollment target is 20 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07536399, a Phase 3 study, has not yet begun recruiting, sponsored by Weill Medical College of Cornell University.
- NOT YET RECRUITING
- Registry status
- Phase 3
- Development phase
- 20 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to learn about the efficacy of using Bone Marrow Aspirate Concentrate (BMAC) during temporomandibular joint (TMJ) arthroscopy compared to standard arthroscopic procedures with corticosteroid (CS) injections in patients with pain (arthralgia) of the temporomandibular joint (TMJ) that has failed to respond to conservative treatment. The main question it aims to answer: Does BMAC injection reduce the amount of inflammation and structural damage in the TMJ? Researchers will compare BMAC injection to corticosteroid injections see if BMAC injection helps . Participants will : * Be randomized to receive either BMAC or CS injection during TMJ arthroscopy * Visit the clinic for 3 follow up visits over 6 months and answer questionnaires * have 2 MRIs of their jaw
Primary Outcome
Participant MRIs will be given a Kellenberger score of 0-13. A higher Kellenberger scores indicate a higher degree of inflammation and damage.
Interventions
- BIOLOGICAL Bone Marrow Aspirate Concentrate
- DRUG Corticosteroid (CS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-04 |
| Est. Completion | 2028-06 |
| Phase | Phase 3 |
What is known before NCT07536399 opens enrollment
NCT07536399 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Bone Marrow Aspirate Concentrate is the first listed.
NCT07536399 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07536399 about?
NCT07536399 is a clinical study titled "Biologic Augmentation of TMJ Arthroscopy Using BMAC". The goal of this clinical trial is to learn about the efficacy of using Bone Marrow Aspirate Concentrate (BMAC) during temporomandibular joint (TMJ) arthroscopy compared to standard arthroscopic procedures with corticosteroid (CS) injections in patients with pain (arthralgia) of the temporomandibula...
What is the current status of trial NCT07536399?
This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 20 participants. The study started on 2026-04. Estimated completion is 2028-06.
What interventions are being tested in trial NCT07536399?
The interventions under investigation include: Bone Marrow Aspirate Concentrate (BIOLOGICAL), Corticosteroid (CS) (DRUG).
Who is sponsoring clinical trial NCT07536399?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07536399's enrollment target sits among peer trials
20 1956th of 2000 higher than 32 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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