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NCT07522190 · ClinicalTrials.gov registry record · NA
Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism
A NA study, sponsored by Stanford University.
- Not yet
- Registry status
- NA
- Development phase
- 140
- Enrollment target
NCT07522190: Clinical Trial NA study, sponsored by Stanford University.
NCT07522190 is a NA study that has not yet begun recruiting, run by Stanford University. The registered enrollment target is 140 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07522190, a NA study, has not yet begun recruiting, sponsored by Stanford University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
Study Summary
The goal of this study is to compare two well-established early autism interventions, Early Start Denver Model (ESDM) and Pivotal Response Treatment (PRT), to better understand which approach is most effective for improving communication skills in young children with autism and which children may benefit most from each treatment. Additionally, after completing either the ESDM or PRT, some participants who meet specific clinical criteria may be offered home-based Developmental Reciprocity Treatment (DRT). The study will include boys and girls 2 to 4 years 11 months old diagnosed with ASD. The main questions this study aims to answer are whether center-based ESDM and center-based PRT improve communication skills in young children with autism, and whether certain children respond better to one treatment approach than the other. Participants will be randomly assigned to either ESDM or PRT for 24 weeks in a center-based program, attend treatment session 4 days per week (\~3 hours/day), complete developmental and autism assessments at baseline, 12 weeks, and 24 weeks, have a parent participate in weekly parent training sessions, and complete follow-up assessments at weeks 36 and 48.
Primary Outcome
A clinician rating that measures how much a child's overall symptoms and functioning have improved or worsened compared to the start of treatment. The CGI ratings will be assessed by a psychologist blind to group assignment and treatment phase, and will specifically focus on social and communication skills.
Interventions
- BEHAVIORAL Early Start Denver Model (ESDM)
- BEHAVIORAL Pivotal Response Treatment (PRT)
- BEHAVIORAL Developmental Reciprocity Treatment (DRT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2027-01 |
| Est. Completion | 2037-01 |
| Phase | NA |
What is known before NCT07522190 opens enrollment
NCT07522190 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 3 interventions - of which Early Start Denver Model (ESDM) is the first listed.
NCT07522190 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07522190 about?
NCT07522190 is a clinical study titled "Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism". The goal of this study is to compare two well-established early autism interventions, Early Start Denver Model (ESDM) and Pivotal Response Treatment (PRT), to better understand which approach is most effective for improving communication skills in young children with autism and which children may be...
What is the current status of trial NCT07522190?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2027-01. Estimated completion is 2037-01.
What interventions are being tested in trial NCT07522190?
The interventions under investigation include: Early Start Denver Model (ESDM) (BEHAVIORAL), Pivotal Response Treatment (PRT) (BEHAVIORAL), Developmental Reciprocity Treatment (DRT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT07522190?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07522190's enrollment target sits among peer trials
140 713th of 2000 higher than 1,281 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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