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NCT07518901 · ClinicalTrials.gov registry record · Phase 4

Nanozymes in Endodontics

A Phase 4 study, sponsored by University of Pennsylvania.

Not yet
Registry status
Phase 4
Development phase
72
Enrollment target

NCT07518901: Clinical Trial Phase 4 study, sponsored by University of Pennsylvania.

NCT07518901 is a Phase 4 study that has not yet begun recruiting, run by University of Pennsylvania. The registered enrollment target is 72 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07518901, a Phase 4 study, has not yet begun recruiting, sponsored by University of Pennsylvania.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
72 participants
Enrollment target

Study Summary

The antimicrobial efficacy and healing potential of clinically approved ferumoxytol nanozymes versus the standard 3% NaOCl irrigant will be evaluated in adults undergoing endodontic treatment. Building on prior protocols that demonstrated ferumoxytol nanozymes antimicrobial activity as a root canal irrigant, ferumoxytol solution will be applied topically, assessment of clinical and radiographical findings will determine its potential as a novel disinfection and its long-term outcome.

Interventions

  • DRUG Control (Standard treatment)
  • DRUG Nanozyme treatment

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2026-06
Est. Completion 2028-06
Phase Phase 4

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT07518901

The ClinicalTrials.gov registry entry for NCT07518901 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Control (Standard treatment) is the first listed.

NCT07518901 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07518901 about?

NCT07518901 is a clinical study titled "Nanozymes in Endodontics". The antimicrobial efficacy and healing potential of clinically approved ferumoxytol nanozymes versus the standard 3% NaOCl irrigant will be evaluated in adults undergoing endodontic treatment. Building on prior protocols that demonstrated ferumoxytol nanozymes antimicrobial activity as a root canal ...

What is the current status of trial NCT07518901?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 72 participants. The study started on 2026-06. Estimated completion is 2028-06.

What interventions are being tested in trial NCT07518901?

The interventions under investigation include: Control (Standard treatment) (DRUG), Nanozyme treatment (DRUG).

Who is sponsoring clinical trial NCT07518901?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.