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NCT07510074 · ClinicalTrials.gov registry record · NA

Modulating Inflammation in Neuro-Trauma

A NA study, sponsored by The University of Texas Health Science Center at San Antonio.

Not yet
Registry status
NA
Development phase
16
Enrollment target

NCT07510074: Clinical Trial NA study, sponsored by The University of Texas Health Science Center at San Antonio.

NCT07510074 is a NA study that has not yet begun recruiting, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07510074, a NA study, has not yet begun recruiting, sponsored by The University of Texas Health Science Center at San Antonio.

NOT YET RECRUITING
Registry status
NA
Development phase
16 participants
Enrollment target

Study Summary

MINT is a single-site, prospective, randomized, double-blind, sham-controlled pilot trial evaluating the safety and feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with moderate to severe traumatic brain injury (GCS 3-12). Participants will be randomized to receive either active taVNS or sham stimulation using the same device. The primary objective is to assess the safety and feasibility of taVNS implementation in the acute TBI setting. Secondary objectives include exploratory measurement of serum inflammatory and neuronal injury biomarkers and assessment of functional outcome using the Extended Glasgow Outcome Scale at hospital discharge.

Primary Outcome

Frequency of adverse events related to tsVNS will be assessed through systematic monitoring

Interventions

  • DEVICE Nurosym taVNS
  • DEVICE Nurosym (sham)

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2026-05
Est. Completion 2027-03
Phase NA

What is known before NCT07510074 opens enrollment

NCT07510074 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Nurosym taVNS is the first listed.

NCT07510074 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07510074 about?

NCT07510074 is a clinical study titled "Modulating Inflammation in Neuro-Trauma". MINT is a single-site, prospective, randomized, double-blind, sham-controlled pilot trial evaluating the safety and feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with moderate to severe traumatic brain injury (GCS 3-12). Participants will be randomized to receiv...

What is the current status of trial NCT07510074?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2026-05. Estimated completion is 2027-03.

What interventions are being tested in trial NCT07510074?

The interventions under investigation include: Nurosym taVNS (DEVICE), Nurosym (sham) (DEVICE).

Who is sponsoring clinical trial NCT07510074?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07510074's enrollment target sits among peer trials

16 1871st of 2000 higher than 120 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07510074, the US trial registry maintained by the National Library of Medicine. NCT07510074 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.