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NCT07498504 · ClinicalTrials.gov registry record
Understanding the Long-term Impact of COVID-19 in Adults
A clinical trial, sponsored by NYU Langone Health.
- Not yet
- Registry status
- 5,205
- Enrollment target
NCT07498504: Clinical Trial study, sponsored by NYU Langone Health.
NCT07498504 is a clinical trial that has not yet begun recruiting, run by NYU Langone Health. The registered enrollment target is 5,205 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07498504 has not yet begun recruiting, sponsored by NYU Langone Health.
- NOT YET RECRUITING
- Registry status
- 5,205 participants
- Enrollment target
Study Summary
Long COVID (LC) affects an estimated 5-10% of individuals with SARS-CoV-2 causing a persistent physical, cognitive, and functional impairment with potentially severe socioeconomic consequences. While RECOVER-Adult cycle 1 established the largest, most comprehensive U.S. adult LC cohort (14,730 participants), key questions remain about long-term disease trajectories, biological mechanisms, and late-emerging complications. RECOVER-Adult cycle 2 will follow selected participants for two years each, focusing on neurocognitive, cardiopulmonary and infection-associated chronic conditions (IACC) such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and autonomic dysfunction. Using a case-cohort design, the study will investigate disease persistence versus resolution, biological mechanisms, and onset of new chronic illnesses, generating critical insights to guide prevention, treatment, and public health policy.
Primary Outcome
The LCRI 11 assesses symptoms such as malaise, brain fog, and fatigue to classify individuals into likely LC, possible LC, or no LC. A score of 11 or greater indicates high-symptom cases of LC.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,205 participants |
| Start Date | 2026-05 |
| Est. Completion | 2030-04 |
What is known before NCT07498504 opens enrollment
NCT07498504 is an observational study that tracks outcomes without assigning an intervention. Its 5,205 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT07498504 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07498504 about?
NCT07498504 is a clinical study titled "Understanding the Long-term Impact of COVID-19 in Adults". Long COVID (LC) affects an estimated 5-10% of individuals with SARS-CoV-2 causing a persistent physical, cognitive, and functional impairment with potentially severe socioeconomic consequences. While RECOVER-Adult cycle 1 established the largest, most comprehensive U.S. adult LC cohort (14,730 parti...
What is the current status of trial NCT07498504?
This trial is currently not yet recruiting. The enrollment target is 5,205 participants. The study started on 2026-05. Estimated completion is 2030-04.
Who is sponsoring clinical trial NCT07498504?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
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