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NCT07487454 · ClinicalTrials.gov registry record · NA
Sham-Controlled Rapid-Acting Neuromodulation for Depression
A NA study, sponsored by University of California, Davis.
- Not yet
- Registry status
- NA
- Development phase
- 264
- Enrollment target
NCT07487454 is a NA study that has not yet begun recruiting, run by University of California, Davis. The registered enrollment target is 264 participants.
The verdict
NCT07487454, a NA study, has not yet begun recruiting, sponsored by University of California, Davis.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 264 participants
- Enrollment target
Study Summary
The goal of this study is to learn whether 5 days of accelerated intermittent theta burst stimulation (iTBS), a rapid form of transcranial magnetic stimulation (TMS), which is a non-invasive procedure that uses magnetic fields to stimulate brain activity, works to treat depression in adults. The main questions it aims to answer are: * Does accelerated iTBS reduce depressive symptoms compared to sham (placebo) stimulation? * Are there measurable brain, biological, and digitally measured emotion changes associated with treatment response? Participants will: * Be randomly assigned to receive either active iTBS or sham stimulation * Receive 10 stimulation sessions per day for 5 consecutive days (total of 50 sessions) * Complete MRI brain scans and EEG recordings before and after treatment * Provide blood and saliva samples to measure biological markers * Complete depression rating scales and questionnaires at baseline, during treatment, and at follow-up visits * Use a secure mobile app to record brief facial and vocal samples during the 5-day treatment and at follow-up visits * Return for follow-up visits at 1 week and at 1, 3, 6, and 12 months after treatment
Interventions
- DEVICE Sham (No Treatment)
- DEVICE intermittent theta burst stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 264 participants |
| Start Date | 2026-12 |
| Est. Completion | 2028-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07487454
The ClinicalTrials.gov registry entry for NCT07487454 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 264 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Sham (No Treatment) is the first listed.
NCT07487454 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07487454 about?
NCT07487454 is a clinical study titled "Sham-Controlled Rapid-Acting Neuromodulation for Depression". The goal of this study is to learn whether 5 days of accelerated intermittent theta burst stimulation (iTBS), a rapid form of transcranial magnetic stimulation (TMS), which is a non-invasive procedure that uses magnetic fields to stimulate brain activity, works to treat depression in adults. The ma...
What is the current status of trial NCT07487454?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 264 participants. The study started on 2026-12. Estimated completion is 2028-05.
What interventions are being tested in trial NCT07487454?
The interventions under investigation include: Sham (No Treatment) (DEVICE), intermittent theta burst stimulation (DEVICE).
Who is sponsoring clinical trial NCT07487454?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
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