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NCT07460440 · ClinicalTrials.gov registry record
SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier
A clinical trial, sponsored by University of Utah.
- Not yet
- Registry status
- 240
- Enrollment target
NCT07460440: Clinical Trial study, sponsored by University of Utah.
NCT07460440 is a clinical trial that has not yet begun recruiting, run by University of Utah. The registered enrollment target is 240 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07460440 has not yet begun recruiting, sponsored by University of Utah.
- NOT YET RECRUITING
- Registry status
- 240 participants
- Enrollment target
Study Summary
The purpose of this study is to test whether combining a unique analytical approach with changes in platelet RNA expression accurately diagnoses lung cancer. Using retrospective platelet transcriptomic data from 522 patients with non-small cell lung cancer (NSCLC, the most common type of lung cancer), an approach that appears to accurately classify lung cancer has been developed. The study will build upon these retrospective analyses to prospectively recruit patients with newly diagnosed lung cancer, obtain platelet RNA samples from whole blood, and perform validation analyses. This research will also test whether this approach accurately distinguishes benign from malignant lung nodules.
Primary Outcome
Sensitivity of the assay in detecting lung cancer
Interventions
- DIAGNOSTIC_TEST Platelet RNA-based assay
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2026-06 |
| Est. Completion | 2028-06 |
What is known before NCT07460440 opens enrollment
NCT07460440 is an observational study that tracks outcomes without assigning an intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Platelet RNA-based assay is the first listed.
NCT07460440 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07460440 about?
NCT07460440 is a clinical study titled "SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier". The purpose of this study is to test whether combining a unique analytical approach with changes in platelet RNA expression accurately diagnoses lung cancer. Using retrospective platelet transcriptomic data from 522 patients with non-small cell lung cancer (NSCLC, the most common type of lung cancer...
What is the current status of trial NCT07460440?
This trial is currently not yet recruiting. The enrollment target is 240 participants. The study started on 2026-06. Estimated completion is 2028-06.
What interventions are being tested in trial NCT07460440?
The interventions under investigation include: Platelet RNA-based assay (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07460440?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
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