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NCT07459803 · ClinicalTrials.gov registry record · NA
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
A NA study, sponsored by Boston University Charles River Campus.
- Not yet
- Registry status
- NA
- Development phase
- 90
- Enrollment target
NCT07459803: Clinical Trial NA study, sponsored by Boston University Charles River Campus.
NCT07459803 is a NA study that has not yet begun recruiting, run by Boston University Charles River Campus. The registered enrollment target is 90 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07459803, a NA study, has not yet begun recruiting, sponsored by Boston University Charles River Campus.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
Study Summary
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an individuals own voice and the movements of their speech muscles, and a motor system that builds and reads out learned motor patterns. The investigators are studying how these systems work together and how they differ across individuals. Investigators will test 90 adults between 18 and 50 years old, including people who stutter, people with dyslexia, and people with typical speech and reading development. Participants will complete several short speech tasks in which the sounds they hear or the movements of their jaw or larynx are briefly changed. These responses will be used to measure each person's speech motor skills and to estimate the settings of a computer model called "SimpleDIVA," which simulates how the brain controls speech. Participants will also complete an MRI scan so investigators can measure the structure and connectivity of different brain regions. These measures will help investigators understand how individual differences in the brain relate to the speech motor control skills we observe. Participants will also complete sessions with noninvasive brain stimulation (transcranial current stimulation, or tCS) to examine how stimulation of specific areas of the brain affects responses during the speech tasks. The knowledge gained from this study will help researchers understand why speech motor skills vary across people and how differences in neural function may contribute to conditions such as stuttering and dyslexia.
Primary Outcome
The amount of compensation to induced F0 and F1 perturbations will be calculated by finding the maximum deviation of the perturbed variable (F0 or F1) from baseline, dividing it by the perturbation size, and then averaging that across all trials of that perturbation.
Interventions
- BEHAVIORAL Unpredictable auditory feedback perturbation: 2 behavioral sessions
- BEHAVIORAL Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions
- BEHAVIORAL Sustained F1 auditory feedback perturbation
- BEHAVIORAL Sustained F0 auditory feedback perturbation
- BEHAVIORAL Reflexive somatosensory perturbation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2026-04 |
| Est. Completion | 2030-03 |
| Phase | NA |
What is known before NCT07459803 opens enrollment
NCT07459803 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 5 interventions - of which Unpredictable auditory feedback perturbation: 2 behavioral sessions is the first listed.
NCT07459803 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07459803 about?
NCT07459803 is a clinical study titled "Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech". This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an individuals own voice and the movements of their speech muscles, and a motor syst...
What is the current status of trial NCT07459803?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2026-04. Estimated completion is 2030-03.
What interventions are being tested in trial NCT07459803?
The interventions under investigation include: Unpredictable auditory feedback perturbation: 2 behavioral sessions (BEHAVIORAL), Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions (BEHAVIORAL), Sustained F1 auditory feedback perturbation (BEHAVIORAL), Sustained F0 auditory feedback perturbation (BEHAVIORAL), Reflexive somatosensory perturbation (BEHAVIORAL).
Who is sponsoring clinical trial NCT07459803?
This trial is sponsored by Boston University Charles River Campus, which has 104 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07459803's enrollment target sits among peer trials
90 941st of 2000 higher than 1,029 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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