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NCT07440446 · ClinicalTrials.gov registry record
Effect of Acetominophen an Gait Fatigue in Multiple Sclerosis
A clinical trial, sponsored by Hunter College of City University of New York.
- Not yet
- Registry status
- 20
- Enrollment target
NCT07440446: Clinical Trial study, sponsored by Hunter College of City University of New York.
NCT07440446 is a clinical trial that has not yet begun recruiting, run by Hunter College of City University of New York. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07440446 has not yet begun recruiting, sponsored by Hunter College of City University of New York.
- NOT YET RECRUITING
- Registry status
- 20 participants
- Enrollment target
Study Summary
The goal of this observational study is to compare the impact of an antipyretic, acetaminophen to a placebo on gait fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: will the antipyretic effects of acetaminophen result in less gait fatigue in persons with MS? Participants will be asked to come for two sessions over a 1 week period. In the first week, subjects will be blind-randomized into either the acetaminophen or placebo group. They will then undergo a test to determine their gait speed by performing two 25 foot walks at their best comfortable pace. The walks will be 1 minute apart. The average speed from those 2 walks will be obtained. Subjects will then take either the acetaminophen or the placebo. Following a 45 minute rest period they will then get on a treadmill and will walk at the previously determined speed for as long as they can. Walking will stop if the subject can no longer maintain the speed or if they wish to no longer continue. The subjects will wear a safety harness at all times during the walk to prevent falls. Heart rate and core body temperature will be measured via skin sensors. One week later the subjects will return and repeat the procedure but this time in the opposite condition. Subjects who took the acetaminophen will take the placebo and subjects who took the placebo will take the acetaminophen. The difference between distance walked in the 2 conditions will be compared.
Interventions
- DRUG 1000mg acetaminophen or placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-03 |
| Est. Completion | 2026-12 |
What is known before NCT07440446 opens enrollment
NCT07440446 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which 1000mg acetaminophen or placebo is the first listed.
NCT07440446 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07440446 about?
NCT07440446 is a clinical study titled "Effect of Acetominophen an Gait Fatigue in Multiple Sclerosis". The goal of this observational study is to compare the impact of an antipyretic, acetaminophen to a placebo on gait fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: will the antipyretic effects of acetaminophen result in less gait fatigue i...
What is the current status of trial NCT07440446?
This trial is currently not yet recruiting. The enrollment target is 20 participants. The study started on 2026-03. Estimated completion is 2026-12.
What interventions are being tested in trial NCT07440446?
The interventions under investigation include: 1000mg acetaminophen or placebo (DRUG).
Who is sponsoring clinical trial NCT07440446?
This trial is sponsored by Hunter College of City University of New York, which has 29 total clinical trials registered on ClinicalTrials.gov.
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