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NCT07422584 · ClinicalTrials.gov registry record
Cytokine Response to Abdominal Wall Reconstruction
A clinical trial of Incisional Ventral Hernia, sponsored by Northwestern University.
- Recruiting
- Registry status
- 25
- Enrollment target
- 1
- Study location
NCT07422584 is a study of Incisional Ventral Hernia that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 25 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07422584, a study of Incisional Ventral Hernia, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, observational translational study of patients undergoing major abdominal wall reconstruction with primary fascial closure. The project integrates perioperative cytokine profiling, direct measurement of intra-abdominal pressure, and detailed clinical outcomes to define the biologic and physiologic consequences of high-tension closure. The study includes three cohorts: 1) Healthy controls (N=5), 2) High-tension fascial closure AWR patients (N=10), 3) Low-tension fascial closure AWR patients (N=10). Fascial closure tension will not be altered for the purpose of the study and will be determined by the operating surgeon as part of routine clinical decision-making.
Conditions Studied
Interventions
- OTHER Not applicable- observational study
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2026-02-03 |
| Est. Completion | 2027-03-05 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07422584
The ClinicalTrials.gov registry entry for NCT07422584 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Incisional Ventral Hernia appearing as the primary indexed condition, and to 1 intervention - of which Not applicable- observational study is the first listed.
NCT07422584 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT07422584 about?
NCT07422584 is a clinical study titled "Cytokine Response to Abdominal Wall Reconstruction". This is a prospective, observational translational study of patients undergoing major abdominal wall reconstruction with primary fascial closure. The project integrates perioperative cytokine profiling, direct measurement of intra-abdominal pressure, and detailed clinical outcomes to define the biol...
What is the current status of trial NCT07422584?
This trial is currently recruiting. The enrollment target is 25 participants. The study started on 2026-02-03. Estimated completion is 2027-03-05.
What conditions does trial NCT07422584 study?
This clinical trial studies the following conditions: Incisional Ventral Hernia.
What interventions are being tested in trial NCT07422584?
The interventions under investigation include: Not applicable- observational study (OTHER).
Who is sponsoring clinical trial NCT07422584?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07422584 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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