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NCT07415681 · ClinicalTrials.gov registry record · Phase 2
GCCC 2578 Randomized Photon vs Proton RT for Newly Diagnosed Gynecologic Primaries
A Phase 2 study, sponsored by University of Maryland, Baltimore.
- Not yet
- Registry status
- Phase 2
- Development phase
- 116
- Enrollment target
NCT07415681: Clinical Trial Phase 2 study, sponsored by University of Maryland, Baltimore.
NCT07415681 is a Phase 2 study that has not yet begun recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 116 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07415681, a Phase 2 study, has not yet begun recruiting, sponsored by University of Maryland, Baltimore.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 116 participants
- Enrollment target
Study Summary
The purpose of study is to compare the side effects of two different forms of radiation for endometrial and cervical cancer. If you decide to enroll in this study, you will be randomized to one of two treatment groups. This study will compare two standard of care treatments: "Conventional" pHoton radiation versus pRoton radiation.
Primary Outcome
To compare patient reported acute gastrointestinal toxicity specifically grade 2 or higher (CTCAE) diarrhea events between IMPT and VMAT for patients receiving pelvic nodal irradiation for newly diagnosed cervical and endometrial cancer.
Interventions
- RADIATION Intensity Modulated Proton Therapy (IMPT)
- RADIATION Volume Modulated Arc Therapy (VMAT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2026-03 |
| Est. Completion | 2033-12 |
| Phase | Phase 2 |
What is known before NCT07415681 opens enrollment
NCT07415681 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 2 interventions - of which Intensity Modulated Proton Therapy (IMPT) is the first listed.
NCT07415681 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07415681 about?
NCT07415681 is a clinical study titled "GCCC 2578 Randomized Photon vs Proton RT for Newly Diagnosed Gynecologic Primaries". The purpose of study is to compare the side effects of two different forms of radiation for endometrial and cervical cancer. If you decide to enroll in this study, you will be randomized to one of two treatment groups. This study will compare two standard of care treatments: "Conventional" pHoton ra...
What is the current status of trial NCT07415681?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 116 participants. The study started on 2026-03. Estimated completion is 2033-12.
What interventions are being tested in trial NCT07415681?
The interventions under investigation include: Intensity Modulated Proton Therapy (IMPT) (RADIATION), Volume Modulated Arc Therapy (VMAT) (RADIATION).
Who is sponsoring clinical trial NCT07415681?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07415681's enrollment target sits among peer trials
116 623rd of 2000 higher than 1,375 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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