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NCT07414992 · ClinicalTrials.gov registry record · Phase 2
A Study of Radiation Therapy and Cemiplimab With or Without Fianlimab In People With Bladder Cancer
A Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.
- Not yet
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
NCT07414992: Clinical Trial Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.
NCT07414992 is a Phase 2 study that has not yet begun recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07414992, a Phase 2 study, has not yet begun recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
Study Summary
The researchers are doing this study to find out whether stereotactic body radiation therapy (SBRT) in combination with immunotherapy (cemiplimab with or without fianlimab) before cystectomy is an effective and safe treatment for people with muscle-invasive bladder cancer (MIBC).
Interventions
- DRUG Cemiplimab
- RADIATION Stereotactic body radiotherapy
- PROCEDURE Radical cystectomy
- DRUG Cemiplimab and Fianlimab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2026-07 |
| Est. Completion | 2028-03 |
| Phase | Phase 2 |
What is known before NCT07414992 opens enrollment
NCT07414992 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 4 interventions - of which Cemiplimab is the first listed.
NCT07414992 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07414992 about?
NCT07414992 is a clinical study titled "A Study of Radiation Therapy and Cemiplimab With or Without Fianlimab In People With Bladder Cancer". The researchers are doing this study to find out whether stereotactic body radiation therapy (SBRT) in combination with immunotherapy (cemiplimab with or without fianlimab) before cystectomy is an effective and safe treatment for people with muscle-invasive bladder cancer (MIBC).
What is the current status of trial NCT07414992?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2026-07. Estimated completion is 2028-03.
What interventions are being tested in trial NCT07414992?
The interventions under investigation include: Cemiplimab (DRUG), Stereotactic body radiotherapy (RADIATION), Radical cystectomy (PROCEDURE), Cemiplimab and Fianlimab (DRUG).
Who is sponsoring clinical trial NCT07414992?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07414992's enrollment target sits among peer trials
44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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