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NCT07404982 · ClinicalTrials.gov registry record · Phase 2
Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter
A Phase 2 study of Joint Replacement Surgery, sponsored by Beth Israel Deaconess Medical Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07404982: Recruiting Phase 2 study of Joint Replacement Surgery, sponsored by Beth Israel Deaconess Medical Center.
NCT07404982 is a Phase 2 study of Joint Replacement Surgery that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07404982, a Phase 2 study of Joint Replacement Surgery, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.
Primary Outcome
Time to residual motor blockade reversal as measured by Bromage score following saline administration and catheter removal, up to a maximum of 60 minutes.
Conditions Studied
Interventions
- DRUG Normal Saline 10 mL Injection
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-02 |
| Est. Completion | 2027-12 |
| Phase | Phase 2 |
What NCT07404982 shows while recruiting
NCT07404982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Joint Replacement Surgery appearing as the primary indexed condition, and to 1 intervention - of which Normal Saline 10 mL Injection is the first listed.
NCT07404982 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07404982 about?
NCT07404982 is a clinical study titled "Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter". The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic s...
What is the current status of trial NCT07404982?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2026-02. Estimated completion is 2027-12.
What conditions does trial NCT07404982 study?
This clinical trial studies the following conditions: Joint Replacement Surgery.
What interventions are being tested in trial NCT07404982?
The interventions under investigation include: Normal Saline 10 mL Injection (DRUG).
Who is sponsoring clinical trial NCT07404982?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07404982 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07404982's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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