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NCT07399496 · ClinicalTrials.gov registry record · NA
Accelerated TMS for Apathy in PD
A NA study, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT07399496 is a NA study that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 15 participants.
The verdict
NCT07399496, a NA study, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
This single-site, open-label pilot study will evaluate the feasibility, tolerability, and preliminary efficacy of accelerated intermittent theta-burst stimulation (iTBS) targeting the dorsomedial prefrontal cortex (dmPFC) for apathy in individuals with Parkinson's Disease (PD). Fifteen participants with PD and clinically significant apathy will undergo six treatment visits over two weeks, receiving eight iTBS sessions per day. Outcomes include adherence, tolerability, changes in apathy (Lille Apathy Rating Scale), functional engagement, and neural target engagement assessed via resting-state fMRI and EEG. Follow-up assessments will occur at two and four weeks post-treatment.
Interventions
- DEVICE Accelerated intermittent theta-burst stimulation (iTBS) rTMS to left dorsomedial prefrontal cortex (dmPFC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-06-01 |
| Est. Completion | 2027-03-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07399496
The ClinicalTrials.gov registry entry for NCT07399496 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Accelerated intermittent theta-burst stimulation (iTBS) rTMS to left dorsomedial prefrontal cortex (dmPFC) is the first listed.
NCT07399496 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07399496 about?
NCT07399496 is a clinical study titled "Accelerated TMS for Apathy in PD". This single-site, open-label pilot study will evaluate the feasibility, tolerability, and preliminary efficacy of accelerated intermittent theta-burst stimulation (iTBS) targeting the dorsomedial prefrontal cortex (dmPFC) for apathy in individuals with Parkinson's Disease (PD). Fifteen participants ...
What is the current status of trial NCT07399496?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2026-06-01. Estimated completion is 2027-03-01.
What interventions are being tested in trial NCT07399496?
The interventions under investigation include: Accelerated intermittent theta-burst stimulation (iTBS) rTMS to left dorsomedial prefrontal cortex (dmPFC) (DEVICE).
Who is sponsoring clinical trial NCT07399496?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
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