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NCT07348263 · ClinicalTrials.gov registry record
EFESO: Study on Juvenile Onset Eosinophilic Fasciitis
A clinical trial of Eosinophilic Fasciitis, sponsored by Meyer Children's Hospital IRCCS.
- Recruiting
- Registry status
- 20
- Enrollment target
- 15
- Study locations
NCT07348263 is a study of Eosinophilic Fasciitis that is actively recruiting participants, run by Meyer Children's Hospital IRCCS. The registered enrollment target is 20 participants. The trial reports 15 study locations across 5 states.
The verdict
NCT07348263, a study of Eosinophilic Fasciitis, is actively recruiting participants, sponsored by Meyer Children's Hospital IRCCS.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 15
- Study locations
Study Summary
Eosinophilic fasciitis is a connective tissue disorder characterized by inflammation of the muscle fasciae, which is very rare in children. In juvenile-onset eosinophilic fasciitis (JEF), there may be severe joint involvement and skin manifestations may be less prevalent than in adults. It represents an important differential diagnosis of both juvenile-onset systemic sclerosis and localized scleroderma, and the correct classification of these patients is necessary to define a targeted diagnostic-therapeutic pathway. The diagnostic criteria proposed for eosinophilic fasciitis in the adult population do not necessarily require confirmation by skin biopsy, currently the "gold standard," which is an invasive procedure for pediatric patients; however, these criteria have never been directly applied to the pediatric population. From a therapeutic point of view, the combination of glucocorticoids and methotrexate is recommended for both adults and pediatric patients, but the data supporting this treatment in children are very limited, and there are no studies comparing the therapeutic approaches currently in use in pediatrics. Finally, there are no studies in the literature documenting the long-term prognosis of these patients in terms of functional limitations, quality of life, or complications related to the disease or treatments.
Conditions Studied
Study Locations (15)
Other
- Children's Hospital Zagreb - Zagreb
- Hamburger Zentrum für Kinder- und Jugendrheumatologie - - Hamburg
- Ruth Rappaport Children's Hospital of Haifa - Haifa
- IRCCS Giannina Gaslini, - Genova
- Università di Udine - Udine
- Iuliu Hatieganu University of Medicine and Pharmacy - Cluj-Napoca
- University Children's Hospital - Ljubljana
- Hospital Sant Joan de Déu, - Barcelona
- Cerrahpasa Medical School, Istanbul University - Istanbul
- Alder Hey Children's Hospital - Liverpool
- Great North Children's Hospital, Newcastle Upon Tyne - Newcastle upon Tyne
Alabama
- University of Alabama at Birmingham - Birmingham
New York
- SUNY Upstate Pediatric Rheumatology - Syracuse
FI
- Meyer Children's Hospital IRCCS - Florence
Stockholm County
- Astrid Lindgren Children's Hospital - Solna
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-05-15 |
| Est. Completion | 2027-05-15 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07348263
The ClinicalTrials.gov registry entry for NCT07348263 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Meyer Children's Hospital IRCCS, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Eosinophilic Fasciitis appearing as the primary indexed condition, and to 0 interventions.
NCT07348263 reports 15 study locations spanning 5 distinct geographic areas - top geographies include Other, Alabama, New York.
Frequently Asked Questions
What is clinical trial NCT07348263 about?
NCT07348263 is a clinical study titled "EFESO: Study on Juvenile Onset Eosinophilic Fasciitis". Eosinophilic fasciitis is a connective tissue disorder characterized by inflammation of the muscle fasciae, which is very rare in children. In juvenile-onset eosinophilic fasciitis (JEF), there may be severe joint involvement and skin manifestations may be less prevalent than in adults. It represent...
What is the current status of trial NCT07348263?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2025-05-15. Estimated completion is 2027-05-15.
What conditions does trial NCT07348263 study?
This clinical trial studies the following conditions: Eosinophilic Fasciitis.
Who is sponsoring clinical trial NCT07348263?
This trial is sponsored by Meyer Children's Hospital IRCCS, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07348263 being conducted?
This trial has 15 study locations across Alabama, New York, FI, Stockholm County. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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