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NCT07306078 · ClinicalTrials.gov registry record · Phase 2
Methylphenidate and Response to Alcohol Cues
A Phase 2 study, sponsored by University of Florida.
- Not yet
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT07306078: Clinical Trial Phase 2 study, sponsored by University of Florida.
NCT07306078 is a Phase 2 study that has not yet begun recruiting, run by University of Florida. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07306078, a Phase 2 study, has not yet begun recruiting, sponsored by University of Florida.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues. The study will observe the effects of methylphenidate or a placebo on neural and craving responses to alcohol cues through fMRI and behavioral testing. Participants will be involved in one remote and two in-person sessions.
Primary Outcome
Whole-brain cue-elicited fMRI responses will be examined by contrasting activation following alcohol images with brain activation following neutral images. Regions-of-interest analysis will focus on anterior cingulate cortex, dorsal striatum, ventral striatum, and amygdala.
Interventions
- DRUG Methylphenidate Pill
- OTHER Placebo Pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-05 |
| Est. Completion | 2028-04 |
| Phase | Phase 2 |
What is known before NCT07306078 opens enrollment
NCT07306078 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 2 interventions - of which Methylphenidate Pill is the first listed.
NCT07306078 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07306078 about?
NCT07306078 is a clinical study titled "Methylphenidate and Response to Alcohol Cues". The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues. The study will observe the effects of methylphenidate or a placebo on neural and craving res...
What is the current status of trial NCT07306078?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2026-05. Estimated completion is 2028-04.
What interventions are being tested in trial NCT07306078?
The interventions under investigation include: Methylphenidate Pill (DRUG), Placebo Pill (OTHER).
Who is sponsoring clinical trial NCT07306078?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07306078's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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