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NCT07293728 · ClinicalTrials.gov registry record · Phase 4

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

A Phase 4 study, sponsored by Oregon Health and Science University.

Not yet
Registry status
Phase 4
Development phase
50
Enrollment target

NCT07293728: Clinical Trial Phase 4 study, sponsored by Oregon Health and Science University.

NCT07293728 is a Phase 4 study that has not yet begun recruiting, run by Oregon Health and Science University. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07293728, a Phase 4 study, has not yet begun recruiting, sponsored by Oregon Health and Science University.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
50 participants
Enrollment target

Study Summary

This is an open-label, randomized feasibility trial in which patients admitted to Oregon Health \& Science University (OHSU) after a pregnancy complicated by preeclampsia who are considering a progestin-only pill contraception postpartum will be randomized to norethindrone or drospirenone for 6 weeks following hospital discharge.

Primary Outcome

Arterial, systolic, and diastolic blood pressure will be compared between norethindrone and drospirenone users. Measured by participants at home and reported in weekly surveys.

Interventions

  • DRUG Drospirenone
  • DRUG Norethindrone 0.35 MG

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-07
Est. Completion 2026-12
Phase Phase 4

What is known before NCT07293728 opens enrollment

NCT07293728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 2 interventions - of which Drospirenone is the first listed.

NCT07293728 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07293728 about?

NCT07293728 is a clinical study titled "A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia". This is an open-label, randomized feasibility trial in which patients admitted to Oregon Health \& Science University (OHSU) after a pregnancy complicated by preeclampsia who are considering a progestin-only pill contraception postpartum will be randomized to norethindrone or drospirenone for 6 week...

What is the current status of trial NCT07293728?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2026-07. Estimated completion is 2026-12.

What interventions are being tested in trial NCT07293728?

The interventions under investigation include: Drospirenone (DRUG), Norethindrone 0.35 MG (DRUG).

Who is sponsoring clinical trial NCT07293728?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07293728's enrollment target sits among peer trials

50 1255th of 2000 higher than 678 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07293728, the US trial registry maintained by the National Library of Medicine. NCT07293728 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.