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NCT07288437 · ClinicalTrials.gov registry record · NA

Deep Brain Stimulation for Spinocerebellar Ataxia

A NA study of Spinocerebellar Ataxia Type 6 and Spinocerebellar Ataxia (SCA), sponsored by University of California, San Francisco.

Recruiting
Registry status
NA
Development phase
5
Enrollment target
2
Study locations

NCT07288437 is a NA study of Spinocerebellar Ataxia Type 6 and Spinocerebellar Ataxia (SCA) that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 5 participants, below the 114-participant average among 3 other Spinocerebellar Ataxia Type 6 trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT07288437, a NA study of Spinocerebellar Ataxia Type 6 and Spinocerebellar Ataxia (SCA), is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
NA
Development phase
5 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical trial is to test the safety of placing Deep Brain Stimulators (DBS) in the cerebellum and using electrical stimulation of that part of the brain to treat symptoms related to the participants spinocerebellar ataxia. Five adults diagnosed with spinocerebellar ataxia type 6 (SCA6) with inadequate cerebellar symptom relief will be implanted with a Medtronic Percept Primary Cell Neurostimulator. The device will be implanted into the dentate nucleus, which is a structure located within the cerebellum that is responsible for controlling movement and balance. Specifically, the investigators will be using adaptive deep brain stimulation (aDBS), which analyzes brain signals and automatically adjusts the strength, timing, and pattern of stimulation according to the patient's needs at any given moment. This study will evaluate the feasibility, safety, and tolerability of aDBS in SCA6 patients.

Interventions

  • DEVICE Deep Brain Stimulation (DBS)

Study Locations (2)

California

  • UCSF Weill Institute for Neurosciences - San Francisco
  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2026-03
Est. Completion 2031-03
Phase NA

What the Registry Record Tells You About NCT07288437

The ClinicalTrials.gov registry entry for NCT07288437 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 114-participant average among 3 other Spinocerebellar Ataxia Type 6 trials with a reported enrollment target (96% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Spinocerebellar Ataxia Type 6 appearing as the primary indexed condition, and to 1 intervention - of which Deep Brain Stimulation (DBS) is the first listed.

NCT07288437 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07288437 about?

NCT07288437 is a clinical study titled "Deep Brain Stimulation for Spinocerebellar Ataxia". The goal of this clinical trial is to test the safety of placing Deep Brain Stimulators (DBS) in the cerebellum and using electrical stimulation of that part of the brain to treat symptoms related to the participants spinocerebellar ataxia. Five adults diagnosed with spinocerebellar ataxia type 6 (S...

What is the current status of trial NCT07288437?

This trial is currently recruiting. It is a NA study. The enrollment target is 5 participants. The study started on 2026-03. Estimated completion is 2031-03.

What conditions does trial NCT07288437 study?

This clinical trial studies the following conditions: Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia (SCA).

What interventions are being tested in trial NCT07288437?

The interventions under investigation include: Deep Brain Stimulation (DBS) (DEVICE).

Who is sponsoring clinical trial NCT07288437?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07288437 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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