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NCT07270302 · ClinicalTrials.gov registry record · Phase 1

Nebulized Nasal Steroids

A Phase 1 study, sponsored by Washington University School of Medicine.

Not yet
Registry status
Phase 1
Development phase
50
Enrollment target

NCT07270302: Clinical Trial Phase 1 study, sponsored by Washington University School of Medicine.

NCT07270302 is a Phase 1 study that has not yet begun recruiting, run by Washington University School of Medicine. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07270302, a Phase 1 study, has not yet begun recruiting, sponsored by Washington University School of Medicine.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
50 participants
Enrollment target

Study Summary

The goal of the proposed project is to assess the efficacy, safety, and patient experience of budesonide administered via the NasoNeb system for medical management of CRS. The authors propose a randomized controlled trial of nebulized budesonide via the NasoNeb compared against budesonide lavage.

Primary Outcome

SNOT-22 is a 22-question survey designed to measure the physical, functional, and emotional consequences of rhinosinusitis. It contains questions regarding symptoms commonly associated with sinonasal disease. Subjects rate each question by using a 0-5 point scale with 0=no problem, 1=very mild problem, 2=mild or slight problem, 3=moderate problem, 4=severe problem, 5=problem as bad as it can be. The SNOT-22 total score ranges from a minimum score of 0 to a maximum score of 110, with higher scor

Interventions

  • COMBINATION_PRODUCT nebulized budesonide via NasoNeb
  • COMBINATION_PRODUCT budesonide lavage via NeilMed

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-12
Est. Completion 2026-05
Phase Phase 1

What is known before NCT07270302 opens enrollment

NCT07270302 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).

The record links to 0 conditions, and to 2 interventions - of which nebulized budesonide via NasoNeb is the first listed.

NCT07270302 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07270302 about?

NCT07270302 is a clinical study titled "Nebulized Nasal Steroids". The goal of the proposed project is to assess the efficacy, safety, and patient experience of budesonide administered via the NasoNeb system for medical management of CRS. The authors propose a randomized controlled trial of nebulized budesonide via the NasoNeb compared against budesonide lavage.

What is the current status of trial NCT07270302?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2025-12. Estimated completion is 2026-05.

What interventions are being tested in trial NCT07270302?

The interventions under investigation include: nebulized budesonide via NasoNeb (COMBINATION_PRODUCT), budesonide lavage via NeilMed (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT07270302?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07270302's enrollment target sits among peer trials

50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07270302, the US trial registry maintained by the National Library of Medicine. NCT07270302 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.