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NCT07260825 · ClinicalTrials.gov registry record · Phase 2
Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial
A Phase 2 study, sponsored by TriHealth.
- Not yet
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
NCT07260825: Clinical Trial Phase 2 study, sponsored by TriHealth.
NCT07260825 is a Phase 2 study that has not yet begun recruiting, run by TriHealth. The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07260825, a Phase 2 study, has not yet begun recruiting, sponsored by TriHealth.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
Study Summary
We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
Primary Outcome
Typical pain with vaginal penetration within last 2 weeks using numeric rating scale
Interventions
- DRUG Estradiol 0.01% Vag Cream
- DRUG testosterone 0.1% and estradiol 0.01% vaginal cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2025-12 |
| Est. Completion | 2026-08 |
| Phase | Phase 2 |
What is known before NCT07260825 opens enrollment
NCT07260825 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Estradiol 0.01% Vag Cream is the first listed.
NCT07260825 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07260825 about?
NCT07260825 is a clinical study titled "Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial". We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
What is the current status of trial NCT07260825?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2025-12. Estimated completion is 2026-08.
What interventions are being tested in trial NCT07260825?
The interventions under investigation include: Estradiol 0.01% Vag Cream (DRUG), testosterone 0.1% and estradiol 0.01% vaginal cream (DRUG).
Who is sponsoring clinical trial NCT07260825?
This trial is sponsored by TriHealth, which has 81 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07260825's enrollment target sits among peer trials
44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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