Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07250854 · ClinicalTrials.gov registry record · Early Phase 1
The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis
A Early Phase 1 study of Biliary Atresia and Kasai, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT07250854 is a Early Phase 1 study of Biliary Atresia and Kasai that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 15 participants, below the 573-participant average among 7 other Biliary Atresia trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07250854, a Early Phase 1 study of Biliary Atresia and Kasai, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
In infants that present with findings concerning for biliary atresia, along with other cholestatic work up which is standard, they will receive a one-time intravenous (IV) dose of Indocyanine Green (ICG). The infant's diapers will subsequently be examined for presence of the ICG, and if present, suggests bile flow. This was described as 97% accurate for assessing biliary patency and we would like to perform a similar study to assess biliary patency in the work up of neonatal cholestasis.
Conditions Studied
Interventions
- DRUG Indocyanine Green
Study Locations (1)
Alabama
- University of Alabama At Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-01-23 |
| Est. Completion | 2027-03 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07250854
The ClinicalTrials.gov registry entry for NCT07250854 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 573-participant average among 7 other Biliary Atresia trials with a reported enrollment target (97% lower). The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Biliary Atresia appearing as the primary indexed condition, and to 1 intervention - of which Indocyanine Green is the first listed.
NCT07250854 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT07250854 about?
NCT07250854 is a clinical study titled "The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis". In infants that present with findings concerning for biliary atresia, along with other cholestatic work up which is standard, they will receive a one-time intravenous (IV) dose of Indocyanine Green (ICG). The infant's diapers will subsequently be examined for presence of the ICG, and if present, sug...
What is the current status of trial NCT07250854?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2026-01-23. Estimated completion is 2027-03.
What conditions does trial NCT07250854 study?
This clinical trial studies the following conditions: Biliary Atresia, Kasai, Cholestasis in Newborn, Cholestasis in Newborn Infant.
What interventions are being tested in trial NCT07250854?
The interventions under investigation include: Indocyanine Green (DRUG).
Who is sponsoring clinical trial NCT07250854?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07250854 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Biliary Atresia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Mapping Disease Pathways for Biliary Atresia
RECRUITING
-
Biliary Atresia Research Network Northeast
RECRUITING
-
Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin
RECRUITING · Phase 1
-
A Prospective Database of Infants With Cholestasis
RECRUITING
-
Biliary Atresia Study in Infants and Children
RECRUITING
-
Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)
ACTIVE NOT RECRUITING · Phase 3
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.