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NCT07228052 · ClinicalTrials.gov registry record · Phase 4
Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department
A Phase 4 study, sponsored by Montefiore Medical Center.
- Not yet
- Registry status
- Phase 4
- Development phase
- 182
- Enrollment target
NCT07228052: Clinical Trial Phase 4 study, sponsored by Montefiore Medical Center.
NCT07228052 is a Phase 4 study that has not yet begun recruiting, run by Montefiore Medical Center. The registered enrollment target is 182 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07228052, a Phase 4 study, has not yet begun recruiting, sponsored by Montefiore Medical Center.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 182 participants
- Enrollment target
Study Summary
This study aims to compare the efficacy of a one-time IM dose of dexamethasone versus a 5-day course of prednisone in adult ED patients presenting with asthma exacerbations. This is a randomized, controlled, double-blind, non-inferiority trial conducted at two urban EDs within the Montefiore Health System.
Primary Outcome
Asthma control will be assessed via administration of the Asthma Control Test (ACT) questionnaire at 4 weeks post-discharge. The ACT questionnaire is comprised of 5 questions which ask participants to recall how asthma symptoms have affected them over the prior 4 weeks. Responses to the 5 questions are rated on a 5-point Likert scale ranging from 1-5, yielding an overall possible scoring range of 5-25. Higher ACT scores are indicative of better asthma control. For this study, an ACT score \>19 i
Interventions
- DRUG Dexamethasone 16mg IM
- DRUG Prednisone 60mg PO
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 182 participants |
| Start Date | 2026-07 |
| Est. Completion | 2026-12 |
| Phase | Phase 4 |
What is known before NCT07228052 opens enrollment
NCT07228052 is an interventional study that assigns participants to a tested intervention. The registered 182 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (65% lower).
The record links to 0 conditions, and to 2 interventions - of which Dexamethasone 16mg IM is the first listed.
NCT07228052 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07228052 about?
NCT07228052 is a clinical study titled "Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department". This study aims to compare the efficacy of a one-time IM dose of dexamethasone versus a 5-day course of prednisone in adult ED patients presenting with asthma exacerbations. This is a randomized, controlled, double-blind, non-inferiority trial conducted at two urban EDs within the Montefiore Health ...
What is the current status of trial NCT07228052?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 182 participants. The study started on 2026-07. Estimated completion is 2026-12.
What interventions are being tested in trial NCT07228052?
The interventions under investigation include: Dexamethasone 16mg IM (DRUG), Prednisone 60mg PO (DRUG).
Who is sponsoring clinical trial NCT07228052?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07228052's enrollment target sits among peer trials
182 464th of 2000 higher than 1,537 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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