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NCT07227389 · ClinicalTrials.gov registry record
Timing of Opioid Administration and Postoperative Respiratory Depression.
A clinical trial, sponsored by Wayne State University.
- Not yet
- Registry status
- 52
- Enrollment target
NCT07227389: Clinical Trial study, sponsored by Wayne State University.
NCT07227389 is a clinical trial that has not yet begun recruiting, run by Wayne State University. The registered enrollment target is 52 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07227389 has not yet begun recruiting, sponsored by Wayne State University.
- NOT YET RECRUITING
- Registry status
- 52 participants
- Enrollment target
Study Summary
The goal of this study is to determine if a relationship can be detected between the administration of an opioid and quantitative respiratory depression in spontaneously breathing non-intubated patients who have undergone general anesthesia and have received perioperative opioids. The primary aim is to determine the temporal effect of opioid administration on respiratory depression as assessed by minute ventilation with a reduction of at least 20% in the percent of predicted minute ventilation. A secondary aim is to determine a dose response of opioid administration and its effect on minute ventilation. The investigators aim to determine the influence of opioid administration on minute ventilation on spontaneously breathing patients during post-anesthesia care unit (PACU) stay.
Primary Outcome
Initiation or cessation of mechanical ventilation
Interventions
- DIAGNOSTIC_TEST Respiratory volume monitoring
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2025-12 |
| Est. Completion | 2029-01-01 |
What is known before NCT07227389 opens enrollment
NCT07227389 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 52 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Respiratory volume monitoring is the first listed.
NCT07227389 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07227389 about?
NCT07227389 is a clinical study titled "Timing of Opioid Administration and Postoperative Respiratory Depression.". The goal of this study is to determine if a relationship can be detected between the administration of an opioid and quantitative respiratory depression in spontaneously breathing non-intubated patients who have undergone general anesthesia and have received perioperative opioids. The primary aim i...
What is the current status of trial NCT07227389?
This trial is currently not yet recruiting. The enrollment target is 52 participants. The study started on 2025-12. Estimated completion is 2029-01-01.
What interventions are being tested in trial NCT07227389?
The interventions under investigation include: Respiratory volume monitoring (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07227389?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
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