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NCT07214844 · ClinicalTrials.gov registry record · NA
A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain
A NA study of Low Back Pain, Chronic, sponsored by Montefiore Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 110
- Enrollment target
- 1
- Study location
NCT07214844: Recruiting NA study of Low Back Pain, Chronic, sponsored by Montefiore Medical Center.
NCT07214844 is a NA study of Low Back Pain, Chronic that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 110 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07214844, a NA study of Low Back Pain, Chronic, is actively recruiting participants, sponsored by Montefiore Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
A research study is being conducted to compare two treatments for long-term low back pain: * One uses the iovera° system, which applies cold to certain nerves in the lower back. * The other is the standard treatment called radiofrequency ablation, which uses heat. The primary objective is to find out which treatment works better to reduce back pain. Participants in this study will be randomly placed in one of the two treatment groups. The clinical research team will check on participant pain levels and overall health before and after the procedure for about 12 months. The entire study will last about 14 months for each participant.
Primary Outcome
Subjects will evaluate their pain in the low back region using an 11-point NRS where 0=no pain and 10=worst possible pain, such that higher scores are associated with greater pain intensity. * Pain intensity scores (using the NRS) measured as "On a scale from 0 to 10, where 0 equals no pain and 10 equals the worst possible pain, how much pain are you experiencing in your low back right now? * Pain intensity scores (using the numeric rating scale; NRS) measured as "On a scale from 0 to 10, where
Conditions Studied
Interventions
- DEVICE Iovera Medial Branch Cryoneurolysis
- PROCEDURE Radiofrequency ablation (RFA)
Study Locations (1)
New York
- Montefiore Multidisciplinary Pain Program - The Bronx
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2026-02 |
| Est. Completion | 2027-03 |
| Phase | NA |
What NCT07214844 shows while recruiting
NCT07214844 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Low Back Pain, Chronic appearing as the primary indexed condition, and to 2 interventions - of which Iovera Medial Branch Cryoneurolysis is the first listed.
NCT07214844 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07214844 about?
NCT07214844 is a clinical study titled "A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain". A research study is being conducted to compare two treatments for long-term low back pain: * One uses the iovera° system, which applies cold to certain nerves in the lower back. * The other is the standard treatment called radiofrequency ablation, which uses heat. The primary objective is to find ...
What is the current status of trial NCT07214844?
This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2026-02. Estimated completion is 2027-03.
What conditions does trial NCT07214844 study?
This clinical trial studies the following conditions: Low Back Pain, Chronic.
What interventions are being tested in trial NCT07214844?
The interventions under investigation include: Iovera Medial Branch Cryoneurolysis (DEVICE), Radiofrequency ablation (RFA) (PROCEDURE).
Who is sponsoring clinical trial NCT07214844?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07214844 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07214844's enrollment target sits among peer trials
110 816th of 2000 higher than 1,176 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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