Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07213544 · ClinicalTrials.gov registry record · Phase 4
Remimazolam vs Propofol in Laser Burn Cases
A Phase 4 study of Burn Scar and Procedural Sedation, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 136
- Enrollment target
- 1
- Study location
NCT07213544: Recruiting Phase 4 study of Burn Scar and Procedural Sedation, sponsored by Medical University of South Carolina.
NCT07213544 is a Phase 4 study of Burn Scar and Procedural Sedation that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 136 participants, above the 36-participant average among 4 other Burn Scar trials with a reported enrollment target (278% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07213544, a Phase 4 study of Burn Scar and Procedural Sedation, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 136 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for burn scars. The primary aim is to assess incidence of respiratory depression, defined as a need for advanced airway maneuvers (jaw thrust/chin lift, insertion of oral or nasal airway, or bag mask ventilation), and hypopnea (respiratory rate \< 8).
Primary Outcome
The incidence of respiratory depression will include need for advanced airway maneuvers, or hypopnea events. Advanced airway maneuvers during the laser therapy procedure may include jaw thrust, chin lift, insertion of oral or nasal airway, or bag mask ventilation. A hypopnea event is defined as a respiratory rate \<8.
Conditions Studied
Interventions
- DRUG Propofol
- DRUG Remimazolam besylate
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 136 participants |
| Start Date | 2025-11-12 |
| Est. Completion | 2027-01-01 |
| Phase | Phase 4 |
What NCT07213544 shows while recruiting
NCT07213544 is an interventional study that assigns participants to a tested intervention. The registered 136 participants enrollment target is mid-sized for trials with a published cap, above the 36-participant average among 4 other Burn Scar trials with a reported enrollment target (278% higher).
The record links to 3 conditions, with Burn Scar appearing as the primary indexed condition, and to 2 interventions - of which Propofol is the first listed.
NCT07213544 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT07213544 about?
NCT07213544 is a clinical study titled "Remimazolam vs Propofol in Laser Burn Cases". This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for burn scars. The primary aim is to assess incidence of respiratory depression, defined as a need for advanced airway maneuvers (jaw thrust/ch...
What is the current status of trial NCT07213544?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 136 participants. The study started on 2025-11-12. Estimated completion is 2027-01-01.
What conditions does trial NCT07213544 study?
This clinical trial studies the following conditions: Burn Scar, Procedural Sedation, Hypertrophic Scarring.
What interventions are being tested in trial NCT07213544?
The interventions under investigation include: Propofol (DRUG), Remimazolam besylate (DRUG).
Who is sponsoring clinical trial NCT07213544?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07213544 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Burn Scar
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01555892 · 136 participants · Phase 1
Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE
- NCT03216525 · 136 participants · Phase 3
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
- NCT04476901 · 136 participants · Phase 2
Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy
- NCT04603898 · 136 participants · NA
Oxalate Formation From Ascorbic Acid
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI