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NCT07212998 · ClinicalTrials.gov registry record · Phase 3

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

A Phase 3 study, sponsored by Jason Sperry.

Not yet
Registry status
Phase 3
Development phase
750
Enrollment target

NCT07212998 is a Phase 3 study that has not yet begun recruiting, run by Jason Sperry. The registered enrollment target is 750 participants.

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The verdict

NCT07212998, a Phase 3 study, has not yet begun recruiting, sponsored by Jason Sperry.

NOT YET RECRUITING
Registry status
Phase 3
Development phase
750 participants
Enrollment target

Study Summary

The Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) trial will be a 5-year (3-year enrollment), open label, phase-3, multi-center, early in-hospital phase randomized trial utilizing burn centers from within the LITES network and will enroll approximately 750 injured adult patients who have suffered large 2nd or 3rd degree thermal burns on at least 20% of their body surface requiring burn resuscitation. The objective is to determine if initiating plasma resuscitation as soon as possible upon arrival to an emergency department or burn unit is the most effective resuscitation for those who have experienced large thermal burns and significantly reduces the morbidity and mortality attributable to post-injury complications as compared to standard in-hospital resuscitation practice.

Interventions

  • BIOLOGICAL Plasma
  • BIOLOGICAL Standard care

Trial Details

FieldValue
Enrollment Target 750 participants
Start Date 2026-08
Est. Completion 2029-09
Phase Phase 3

Sponsor

Jason Sperry

10 total trials

What the Registry Record Tells You About NCT07212998

The ClinicalTrials.gov registry entry for NCT07212998 describes a study currently listed as not yet recruiting, categorized as Phase 3. The registered enrollment target is 750 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jason Sperry, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Plasma is the first listed.

NCT07212998 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07212998 about?

NCT07212998 is a clinical study titled "Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial". The Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) trial will be a 5-year (3-year enrollment), open label, phase-3, multi-center, early in-hospital phase randomized trial utilizing burn centers from within the LITES network and will enroll approxima...

What is the current status of trial NCT07212998?

This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 750 participants. The study started on 2026-08. Estimated completion is 2029-09.

What interventions are being tested in trial NCT07212998?

The interventions under investigation include: Plasma (BIOLOGICAL), Standard care (BIOLOGICAL).

Who is sponsoring clinical trial NCT07212998?

This trial is sponsored by Jason Sperry, which has 10 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.