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NCT07210697 · ClinicalTrials.gov registry record · Phase 3
Orthodontic Pain Alleviation With Chewing Gum
A Phase 3 study, sponsored by West Virginia University.
- Not yet
- Registry status
- Phase 3
- Development phase
- 60
- Enrollment target
NCT07210697: Clinical Trial Phase 3 study, sponsored by West Virginia University.
NCT07210697 is a Phase 3 study that has not yet begun recruiting, run by West Virginia University. The registered enrollment target is 60 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07210697, a Phase 3 study, has not yet begun recruiting, sponsored by West Virginia University.
- NOT YET RECRUITING
- Registry status
- Phase 3
- Development phase
- 60 participants
- Enrollment target
Study Summary
The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience. The long-term goal is to enable clinicians to decide whether prescription of chewing gum at the placement of orthodontic appliances can improve patient experience with orthodontic treatment. In specific, a total of 60 patients under the age of 18 will be recruited for the study. Consent will be signed by both the child patient and the parents. 30 patients will be asked to chew xylitol gum and the other 30 patients will refrain from chewing gum and serve as the control group. At the appointment for insertion of orthodontic appliances, patients will be instructed to chew one serving or two pieces of xylitol gum three times per day for a total of six grams of xylitol per day. Patients will participate in a survey at the following timepoints- 4 hours, 24 hours, 48 hours and 7 days. The expectation is that this study will determine the effectiveness of using xylitol to decrease pain in orthodontic patients.
Primary Outcome
Assessment of pain on a visual analogue scale with the scale being 0= very comfortable and 10= severe discomfort with 10 being the worst outcome.
Interventions
- DRUG Xylitol Gum
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-10 |
| Est. Completion | 2026-03 |
| Phase | Phase 3 |
What is known before NCT07210697 opens enrollment
NCT07210697 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Xylitol Gum is the first listed.
NCT07210697 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07210697 about?
NCT07210697 is a clinical study titled "Orthodontic Pain Alleviation With Chewing Gum". The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience. The long-term goal is to enable clinicians to decide whether prescription of chewing gum at the placement of orthodontic appliances can improve patie...
What is the current status of trial NCT07210697?
This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2025-10. Estimated completion is 2026-03.
What interventions are being tested in trial NCT07210697?
The interventions under investigation include: Xylitol Gum (DRUG).
Who is sponsoring clinical trial NCT07210697?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07210697's enrollment target sits among peer trials
60 1804th of 2000 higher than 177 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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