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NCT07204275 · ClinicalTrials.gov registry record · Phase 2
A Study to Evaluate Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
A Phase 2 study of Primary Membranous Nephropathy, sponsored by Vertex Pharmaceuticals Incorporated.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 176
- Enrollment target
- 20
- Study locations
NCT07204275 is a Phase 2 study of Primary Membranous Nephropathy that is actively recruiting participants, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 176 participants, above the 114-participant average among 8 other Primary Membranous Nephropathy trials with a reported enrollment target (54% higher). The trial reports 20 study locations across 12 states.
The verdict
NCT07204275, a Phase 2 study of Primary Membranous Nephropathy, is actively recruiting participants, sponsored by Vertex Pharmaceuticals Incorporated.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 176 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).
Conditions Studied
Interventions
- DRUG Tacrolimus
- DRUG Povetacicept
Study Locations (20)
Texas
- El Paso Kidney Specialists - El Paso
- Provecta Research Network - Houston
- DaVita Clinical Research Houston - Houston
- Davita Clinical Research San Antonio - San Antonio
Florida
- Bioresearch Partner - Miami
- CTR Oakwater, LLC - Orlando
- Clinical Site Partners, LLC - Orlando - Winter Park
California
- Academic Medical Research Institute (AMRI) - Los Angeles
- Valiance Clinical Research - Internal Medicine - Tarzana
Georgia
- DaVita Clinical Research Columbus - Columbus
- Georgia Nephrology - Lawrenceville
South Carolina
- Carolina Nephrology Greenville - Greenville
- Carolina Nephrology, PA - Spartanburg
Alabama
- Renal Associates - Montgomery
Arizona
- Southwest Kidney Institute, PLC (SKI) - Surprise - Surprise
Colorado
- Western Nephrology & Metabolic Bone Disease PC - Arvada
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 176 participants |
| Start Date | 2025-09-30 |
| Est. Completion | 2028-12-29 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07204275
The ClinicalTrials.gov registry entry for NCT07204275 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 176 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 114-participant average among 8 other Primary Membranous Nephropathy trials with a reported enrollment target (54% higher). The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Primary Membranous Nephropathy appearing as the primary indexed condition, and to 2 interventions - of which Tacrolimus is the first listed.
NCT07204275 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Texas, Florida, California.
Frequently Asked Questions
What is clinical trial NCT07204275 about?
NCT07204275 is a clinical study titled "A Study to Evaluate Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)". The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).
What is the current status of trial NCT07204275?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 176 participants. The study started on 2025-09-30. Estimated completion is 2028-12-29.
What conditions does trial NCT07204275 study?
This clinical trial studies the following conditions: Primary Membranous Nephropathy.
What interventions are being tested in trial NCT07204275?
The interventions under investigation include: Tacrolimus (DRUG), Povetacicept (DRUG).
Who is sponsoring clinical trial NCT07204275?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07204275 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.