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NCT07131592 · ClinicalTrials.gov registry record · Phase 4

Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

A Phase 4 study of Breast Reductions and Drain Output After Breast Reduction Surgery, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
Phase 4
Development phase
160
Enrollment target
1
Study location

NCT07131592 is a Phase 4 study of Breast Reductions and Drain Output After Breast Reduction Surgery that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 160 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07131592, a Phase 4 study of Breast Reductions and Drain Output After Breast Reduction Surgery, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
Phase 4
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned to receive either intravenous TXA or no TXA during surgery. Additionally, one breast will receive TXA through the surgical drain, while the other will receive saline. This approach allows to compare the effects of TXA on fluid buildup and healing. The goal is to improve recovery and reduce complications after breast reduction surgery.

Interventions

  • DRUG IV TXA
  • DRUG Topical TXA
  • DRUG Topical saline

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2025-11-18
Est. Completion 2027-08-31
Phase Phase 4

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT07131592

The ClinicalTrials.gov registry entry for NCT07131592 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Breast Reductions appearing as the primary indexed condition, and to 3 interventions - of which IV TXA is the first listed.

NCT07131592 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07131592 about?

NCT07131592 is a clinical study titled "Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery". This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned to receive either intravenous TXA or no TXA during surgery. Additionally, one breast will receive TXA...

What is the current status of trial NCT07131592?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 160 participants. The study started on 2025-11-18. Estimated completion is 2027-08-31.

What conditions does trial NCT07131592 study?

This clinical trial studies the following conditions: Breast Reductions, Drain Output After Breast Reduction Surgery.

What interventions are being tested in trial NCT07131592?

The interventions under investigation include: IV TXA (DRUG), Topical TXA (DRUG), Topical saline (DRUG).

Who is sponsoring clinical trial NCT07131592?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07131592 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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